Claim · model-written summary
A host protein was enriched with brome mosaic virus RNA polymerase activity.
- Taxon
- barley
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Hordeum vulgaret0 - Interactor
- BMV
Brome mosaic viruse0pathogen - Gene
- A host proteine0
- Outcome
- BMV RdRp activitye0
Verbatim
e0“A host protein was specifically and proportionally enriched with BMV RdRp activity through several purification steps.”
t0“from brome mosaic virus (BMV)-infected barley.”
Title
Characterization of a host protein associated with brome mosaic virus RNA-dependent RNA polymerase.
R Quadt; C C Kao; K S Browning; et al. Proceedings of the National Academy of Sciences 1993. doi:10.1073/pnas.90.4.1498
Other claims from this paper (4)
- Observation The polymerase-associated host protein reacted with antiserum against wheat germ eIF-3.
- Observation The host protein and related translation factor proteins bound specifically to viral protein 2a.
- Intervention effect Adding wheat germ eIF-3 or p41 stimulated negative-strand viral RNA synthesis threefold.
- Mechanism The authors infer that a barley p41 analog associates with viral polymerase and participates in RNA replication.