Paper · 1999 · FEBS Letters

Evolutionally conserved plant homologue of the Bax Inhibitor‐1 (BI‐1) gene capable of suppressing Bax‐induced cell death in yeast1

Maki Kawai; Ling Pan; John C. Reed; et al.

6
claims
10
verbatim quotes
146
citations
1
research areas
✓
Open access

Abstract

The plant homologue of Bax Inhibitor-1, a gene described to suppress the cell death induced by Bax gene expression in yeast, was isolated from Oryza sativa L. (rice) and Arabidopsis. The amino acid sequence of the predicted protein was well conserved in both animal and plant (45% in amino acids) and contained six or seven membrane-spanning segments. Northern blot analysis showed that OsBI-1 transcripts were present in all tissues examined. The OsBI-1 cDNA suppressed cell death induced by mammalian Bax in yeast, suggesting functional conservation of this BI-1 homologue in the plant kingdom.

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Claims 6

Observationobservedoriginal resultmeasured

Claim · model-written summary

A Bax Inhibitor-1 homologue was isolated from rice.

Taxon
Oryza sativa L. (rice)Oryza sativae0
Gene
Bax Inhibitor-1e0
Outcome
was isolatede0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“The plant homologue of Bax Inhibitor-1, a gene described to suppress the cell death induced by Bax gene expression in yeast, was isolated from Oryza sativa L. (rice) and Arabidopsis”

✓ located verbatim in the source · abstract, characters 0–181 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

A Bax Inhibitor-1 homologue was isolated from Arabidopsis.

Taxon
ArabidopsisArabidopsise0
Gene
Bax Inhibitor-1e0
Outcome
was isolatede0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Arabidopsis
Arabidopsis · Taxon · picture of the genus (one of its species)Original uploader was Brona at en.wikipedia . User:Roepers at nl.wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“The plant homologue of Bax Inhibitor-1, a gene described to suppress the cell death induced by Bax gene expression in yeast, was isolated from Oryza sativa L. (rice) and Arabidopsis”

✓ located verbatim in the source · abstract, characters 0–181 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The predicted BI-1 protein sequence was 45% conserved between animals and plants.

Taxon
Oryza sativa L. (rice)Oryza sativae1
Gene
Bax Inhibitor-1e1
Outcome
amino acid sequencee0
Value
45% in amino acidse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“The amino acid sequence of the predicted protein was well conserved in both animal and plant (45% in amino acids)”

✓ located verbatim in the source · abstract, characters 183–296 · show in text ↑
e1

“The plant homologue of Bax Inhibitor-1, a gene described to suppress the cell death induced by Bax gene expression in yeast, was isolated from Oryza sativa L. (rice) and Arabidopsis”

✓ located verbatim in the source · abstract, characters 0–181 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The predicted protein contained six or seven membrane-spanning segments.

Taxon
Oryza sativa L. (rice)Oryza sativae1
Gene
Bax Inhibitor-1e1
Outcome
membrane-spanning segmentse0
Value
six or sevene0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“contained six or seven membrane-spanning segments”

✓ located verbatim in the source · abstract, characters 301–350 · show in text ↑
e1

“The plant homologue of Bax Inhibitor-1, a gene described to suppress the cell death induced by Bax gene expression in yeast, was isolated from Oryza sativa L. (rice) and Arabidopsis”

✓ located verbatim in the source · abstract, characters 0–181 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

OsBI-1 transcripts occurred in every tissue examined.

Taxon
Oryza sativa L. (rice)Oryza sativae1
Gene
OsBI-1e0
Outcome
transcripts were present in all tissues examinede0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“OsBI-1 transcripts were present in all tissues examined”

✓ located verbatim in the source · abstract, characters 387–442 · show in text ↑
e1

“The plant homologue of Bax Inhibitor-1, a gene described to suppress the cell death induced by Bax gene expression in yeast, was isolated from Oryza sativa L. (rice) and Arabidopsis”

✓ located verbatim in the source · abstract, characters 0–181 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

OsBI-1 cDNA suppressed mammalian Bax-induced cell death in yeast.

Taxon
Oryza sativa L. (rice)Oryza sativae1
Treatment
OsBI-1 cDNAe0
Gene
OsBI-1e0
Outcome
cell death induced by mammalian Bax in yeaste0
Direction
suppressede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“The OsBI-1 cDNA suppressed cell death induced by mammalian Bax in yeast”

✓ located verbatim in the source · abstract, characters 444–515 · show in text ↑
e1

“The plant homologue of Bax Inhibitor-1, a gene described to suppress the cell death induced by Bax gene expression in yeast, was isolated from Oryza sativa L. (rice) and Arabidopsis”

✓ located verbatim in the source · abstract, characters 0–181 · show in text ↑