Abstract
BACKGROUND: Embelia ribes Burm is widely used medicinal plant for the treatment of different types of disorders in the Indian traditional systems of medicine. OBJECTIVE: The present work was aimed to optimize the extraction parameters of embelin from E. ribes fruits and also to quantify embelin content in different extracts of the plant. MATERIALS AND METHODS: Optimization of extraction parameters such as solvent: drug ratio, temperature and time were carried out by response surface methodology (RSM). Quantitative estimation of embelin in different extracts of E. ribes fruits was done through high performance liquid chromatography. RESULTS: The optimal conditions determined for extraction of embelin through RSM were; extraction time (27.50 min), extraction temperature 45°C and solvent: drug ratio (8:1). Under the optimized conditions, the embelin yield (32.71%) was equitable to the expected yield (31.07%, P > 0.05). These results showed that the developed model is satisfactory and suitable for the extraction process of embelin. The analysis of variance showed a high goodness of model fit and the accomplishment of the RSM method for improving embelin extraction from the fruits of E. ribes. CONCLUSION: It is concluded that this may be a useful method for the extraction and quantitative estimation of embelin from the fruits of E. ribes.
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Claims 5
Claim · model-written summary
The optimal RSM extraction time for embelin from Embelia ribes fruits is 27.50 min.
- Taxon
- Embelia ribes
Embelia ribest0 - Outcome
- extraction timee1
- Value
- 27.50 mine1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Embelia ribes”
e1“The optimal conditions determined for extraction of embelin through RSM were; extraction time (27.50 min), extraction temperature 45°C and solvent: drug ratio (8:1)”
Claim · model-written summary
The optimal RSM extraction temperature for embelin from Embelia ribes fruits is 45°C.
- Taxon
- Embelia ribesEmbelia ribest0
- Outcome
- extraction temperaturee1
- Value
- 45°Ce1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Embelia ribes”
e1“The optimal conditions determined for extraction of embelin through RSM were; extraction time (27.50 min), extraction temperature 45°C and solvent: drug ratio (8:1)”
Claim · model-written summary
The optimal RSM solvent to drug ratio for embelin from Embelia ribes fruits is 8:1.
- Taxon
- Embelia ribesEmbelia ribest0
- Outcome
- solvent: drug ratioe1
- Value
- 8:1e1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Embelia ribes”
e1“The optimal conditions determined for extraction of embelin through RSM were; extraction time (27.50 min), extraction temperature 45°C and solvent: drug ratio (8:1)”
Claim · model-written summary
Under the optimized conditions, the embelin yield of Embelia ribes (32.71%) was not significantly different from the expected yield.
- Taxon
- Embelia ribesEmbelia ribest0
- Treatment
- optimized conditionse1
- Outcome
- embelin yielde1
- Value
- 32.71%e1
- Qualifier
- 31.07%, P > 0.05e1
- Comparator
- expected yielde1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Embelia ribes”
e1“Under the optimized conditions, the embelin yield (32.71%) was equitable to the expected yield (31.07%, P > 0.05)”
Claim · model-written summary
The RSM model for embelin extraction from E. ribes fruits shows a high goodness of fit and is satisfactory for the extraction process.
- Taxon
- E. ribesEmbelia ribese2
- Organ / stage
- fruitse2
- Outcome
- goodness of model fite2
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“These results showed that the developed model is satisfactory and suitable for the extraction process of embelin”
e2“The analysis of variance showed a high goodness of model fit and the accomplishment of the RSM method for improving embelin extraction from the fruits of E. ribes”