Abstract
Colchicine at the concentration of 10-4 M completely inhibited phragmoplast formation of culcured carrot cells and produced large spherical cells, whereas griseofulvin and caffeine produced large but irregular cells. In the presence of griseofulvin or a lower concentration of colchicine (10-5 M), septum formation was incomplete and highly irregular cross walls were formed. Caffeine also inhibited normal septum formation, but it did not induce intricate cross walls.Inhibition of cytokinesis by 10-4 M colchicine could be the result of the loss of cytoplasmic microtubules in the phragmoplast region. In cells treated with 10-5 M colchicine or 5 × 10-5-10-3 M griseofulvin, a considerable number of microtubules remained but the array of vesicles in the phragmoplast region was markedly disordered. Caffeine seemed to inhibit fusion of the vesicles aligned in the phragmoplast region.
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Claims 12
Claim · model-written summary
10-4 M colchicine inhibited phragmoplast formation.
- Taxon
- carrot
Daucus carotae0 - Treatment
- Colchicine at the concentration of 10-4 Me0
- Outcome
- phragmoplast formatione0
- Direction
- completely inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Colchicine at the concentration of 10-4 M completely inhibited phragmoplast formation of culcured carrot cells and produced large spherical cells”
Claim · model-written summary
10-4 M colchicine produced large spherical cells.
- Taxon
- carrotDaucus carotae0
- Treatment
- Colchicine at the concentration of 10-4 Me0
- Outcome
- large spherical cellse0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Colchicine at the concentration of 10-4 M completely inhibited phragmoplast formation of culcured carrot cells and produced large spherical cells”
Claim · model-written summary
Griseofulvin produced large irregular cells.
- Taxon
- CarrotDaucus carotat0
- Treatment
- griseofulvine0
- Outcome
- large but irregular cellse0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“griseofulvin and caffeine produced large but irregular cells.”
t0“Carrot”
Claim · model-written summary
Caffeine produced large irregular cells.
- Taxon
- CarrotDaucus carotat0
- Treatment
- caffeinee0
- Outcome
- large but irregular cellse0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“griseofulvin and caffeine produced large but irregular cells.”
t0“Carrot”
Claim · model-written summary
Griseofulvin caused incomplete septa and irregular cross walls.
- Taxon
- CarrotDaucus carotat0
- Treatment
- griseofulvine0
- Outcome
- septum formation was incomplete and highly irregular cross walls were formede0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In the presence of griseofulvin or a lower concentration of colchicine (10-5 M), septum formation was incomplete and highly irregular cross walls were formed.”
t0“Carrot”
Claim · model-written summary
10-5 M colchicine caused incomplete septa and irregular cross walls.
- Taxon
- CarrotDaucus carotat0
- Treatment
- colchicine (10-5 M)e0
- Outcome
- septum formation was incomplete and highly irregular cross walls were formede0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In the presence of griseofulvin or a lower concentration of colchicine (10-5 M), septum formation was incomplete and highly irregular cross walls were formed.”
t0“Carrot”
Claim · model-written summary
Caffeine inhibited normal septum formation.
- Taxon
- CarrotDaucus carotat0
- Treatment
- Caffeinee0
- Outcome
- normal septum formatione0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Caffeine also inhibited normal septum formation, but it did not induce intricate cross walls.”
t0“Carrot”
Claim · model-written summary
Caffeine did not induce intricate cross walls.
- Taxon
- CarrotDaucus carotat0
- Treatment
- Caffeinee0
- Outcome
- intricate cross wallse0
- Direction
- did not inducee0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Caffeine also inhibited normal septum formation, but it did not induce intricate cross walls.”
t0“Carrot”
Claim · model-written summary
Loss of phragmoplast microtubules may explain colchicine inhibition of cytokinesis.
- Taxon
- CarrotDaucus carotat0
- Treatment
- 10-4 M colchicinee0
- Outcome
- Inhibition of cytokinesise0
- Qualifier
- loss of cytoplasmic microtubules in the phragmoplast regione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Inhibition of cytokinesis by 10-4 M colchicine could be the result of the loss of cytoplasmic microtubules in the phragmoplast region.”
t0“Carrot”
Claim · model-written summary
Microtubules remained after 10-5 M colchicine, while phragmoplast vesicles were disordered.
- Taxon
- CarrotDaucus carotat0
- Treatment
- 10-5 M colchicinee0
- Outcome
- a considerable number of microtubules remained but the array of vesicles in the phragmoplast region was markedly disorderede0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In cells treated with 10-5 M colchicine or 5 × 10-5-10-3 M griseofulvin, a considerable number of microtubules remained but the array of vesicles in the phragmoplast region was markedly disordered.”
t0“Carrot”
Claim · model-written summary
Microtubules remained after griseofulvin, while phragmoplast vesicles were disordered.
- Taxon
- CarrotDaucus carotat0
- Treatment
- 5 × 10-5-10-3 M griseofulvine0
- Outcome
- a considerable number of microtubules remained but the array of vesicles in the phragmoplast region was markedly disorderede0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In cells treated with 10-5 M colchicine or 5 × 10-5-10-3 M griseofulvin, a considerable number of microtubules remained but the array of vesicles in the phragmoplast region was markedly disordered.”
t0“Carrot”
Claim · model-written summary
Caffeine appeared to inhibit phragmoplast vesicle fusion.
- Taxon
- CarrotDaucus carotat0
- Treatment
- Caffeinee0
- Outcome
- fusion of the vesiclese0
- Direction
- inhibite0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Caffeine seemed to inhibit fusion of the vesicles aligned in the phragmoplast region.”
t0“Carrot”