Paper · 2005 · Proceedings of the Royal Society B Biological Sciences

Farm Scale Evaluations of spring-sown genetically modified herbicide-tolerant crops: a statistical assessment

Suzanne J Clark; Peter Rothery; Joe N Perry

12
claims
24
verbatim quotes
20
citations
1
research areas
✓
Open access

Abstract

Primary results from the Farm Scale Evaluations (FSEs) of spring-sown genetically modified herbicide-tolerant crops were published in 2003. We provide a statistical assessment of the results for count data, addressing issues of sample size (n), efficiency, power, statistical significance, variability and model selection. Treatment effects were consistent between rare and abundant species. Coefficients of variation averaged 73% but varied widely. High variability in vegetation indicators was usually offset by large n and treatment effects, whilst invertebrate indicators often had smaller n and lower variability; overall, achieved power was broadly consistent across indicators. Inferences about treatment effects were robust to model misspecification, justifying the statistical model adopted. As expected, increases in n would improve detectability of effects whilst, for example, halving n would have resulted in a loss of significant results of about the same order. 40% of the 531 published analyses had greater than 80% power to detect a 1.5-fold effect; reducing n by one-third would most likely halve the number of analyses meeting this criterion. Overall, the data collected vindicated the initial statistical power analysis and the planned replication. The FSEs provide a valuable database of variability and estimates of power under various sample size scenarios to aid planning of more efficient future studies.

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Claims 12

Observationobservedoriginal resultmeasured

Claim · model-written summary

Treatment effects of the herbicide-tolerant crop regimes were consistent between rare and abundant species.

Taxon
herbicide-tolerant cropst0
Outcome
Treatment effects were consistent between rare and abundant speciese1

Verbatim

e1

“Treatment effects were consistent between rare and abundant species”

✓ located verbatim in the source · abstract, characters 323–390 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Coefficients of variation of the count data averaged 73% but varied widely.

Taxon
herbicide-tolerant cropst0
Outcome
Coefficients of variatione2
Value
73%e2
Qualifier
varied widelye2

Verbatim

e2

“Coefficients of variation averaged 73% but varied widely”

✓ located verbatim in the source · abstract, characters 392–448 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Observationobservedoriginal resultmeasured

Claim · model-written summary

High variability in vegetation indicators was usually offset by large sample size and treatment effects.

Taxon
herbicide-tolerant cropst0
Outcome
variability in vegetation indicators was usually offset by large n and treatment effectse3

Verbatim

e3

“High variability in vegetation indicators was usually offset by large n and treatment effects”

✓ located verbatim in the source · abstract, characters 450–543 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Observationobservedoriginal resultmeasured

Claim · model-written summary

Invertebrate indicators often had smaller sample sizes and lower variability.

Taxon
herbicide-tolerant cropst0
Outcome
invertebrate indicators often had smaller n and lower variabilitye4

Verbatim

e4

“invertebrate indicators often had smaller n and lower variability”

✓ located verbatim in the source · abstract, characters 552–617 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Observationobservedoriginal resultmeasured

Claim · model-written summary

Achieved power was broadly consistent across indicators.

Taxon
herbicide-tolerant cropst0
Outcome
achieved powere5
Qualifier
was broadly consistent across indicatorse5

Verbatim

e5

“overall, achieved power was broadly consistent across indicators”

✓ located verbatim in the source · abstract, characters 619–683 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Observationobservedoriginal resultmeasured

Claim · model-written summary

Inferences about treatment effects were robust to model misspecification.

Taxon
herbicide-tolerant cropst0
Outcome
Inferences about treatment effects were robust to model misspecificatione6

Verbatim

e6

“Inferences about treatment effects were robust to model misspecification”

✓ located verbatim in the source · abstract, characters 685–757 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Associationauthor interpretationoriginal resultpositivesimulated

Claim · model-written summary

Increasing sample size would improve the detectability of effects.

Taxon
herbicide-tolerant cropst0
Treatment
increases in ne7
Outcome
detectability of effectse7
Direction
improvee7

Verbatim

e7

“increases in n would improve detectability of effects”

✓ located verbatim in the source · abstract, characters 814–867 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Associationauthor interpretationoriginal resultnegativesimulated

Claim · model-written summary

Halving sample size would have resulted in a loss of significant results of about the same order.

Taxon
herbicide-tolerant cropst0
Treatment
halving ne0
Outcome
significant resultse0
Direction
resulted in a losse0

Verbatim

e0

“halving n would have resulted in a loss of significant results of about the same order”

✓ located verbatim in the source · abstract, characters 889–975 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Observationobservedoriginal resultmeasured

Claim · model-written summary

40% of the 531 published analyses had greater than 80% power to detect a 1.5-fold effect.

Taxon
herbicide-tolerant cropst0
Outcome
published analyses had greater than 80% power to detect a 1.5-fold effecte0
Value
40%e0

Verbatim

e0

“40% of the 531 published analyses had greater than 80% power to detect a 1.5-fold effect”

✓ located verbatim in the source · abstract, characters 977–1065 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Associationauthor interpretationoriginal resultnegativeprojected

Claim · model-written summary

Reducing sample size by one-third would most likely halve the number of analyses with adequate power.

Taxon
herbicide-tolerant cropst0
Treatment
reducing n by one-thirde0
Outcome
number of analyses meeting this criterione0
Direction
halvee0
Qualifier
most likelye0

Verbatim

e0

“reducing n by one-third would most likely halve the number of analyses meeting this criterion”

✓ located verbatim in the source · abstract, characters 1067–1160 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Observationauthor interpretationoriginal resultmeasured

Claim · model-written summary

The data collected vindicated the initial statistical power analysis and the planned replication.

Taxon
herbicide-tolerant cropst0
Outcome
the data collected vindicated the initial statistical power analysis and the planned replicatione0

Verbatim

e0

“Overall, the data collected vindicated the initial statistical power analysis and the planned replication”

✓ located verbatim in the source · abstract, characters 1162–1267 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑

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Recommendationauthor interpretationoriginal resultbasis n/a

Claim · model-written summary

The farm-scale evaluation data form a valuable database of variability and power estimates for planning future studies.

Taxon
herbicide-tolerant cropst0
Outcome
a valuable database of variability and estimates of power under various sample size scenariose0

Verbatim

e0

“The FSEs provide a valuable database of variability and estimates of power under various sample size scenarios to aid planning of more efficient future studies”

✓ located verbatim in the source · abstract, characters 1269–1428 · show in text ↑
t0

“spring-sown genetically modified herbicide-tolerant crops”

✓ located verbatim in the source · title, characters 26–83 · show in text ↑