Abstract
Potato pectin falls to Phytophthora Phytophthora infestans is a plant oomycete pathogen that drove the potato famines of the 1800s and continues to afflict potato fields today. The polysaccharide pectin makes up about a third of the cell wall in potatoes. Sabbadin et al . identified a family of lytic polysaccharide monooxygenases (LMPOs) that cleave pectin and are upregulated in P. infestans during infection. Silencing the relevant LMPO gene successfully inhibited P. infestans infections. These findings open doors for disease intervention targets and for biotech applications. —PJH
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Claims 3
Claim · model-written summary
A family of pectin-cleaving lytic polysaccharide monooxygenases was identified in the pathogen.
- Taxon
- potato
Solanum tuberosume2 - Interactor
- P. infestans
Phytophthora infestanse1pathogen - Gene
- lytic polysaccharide monooxygenases (LMPOs)e0
- Outcome
- family of lytic polysaccharide monooxygenases (LMPOs) that cleave pectine0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“identified a family of lytic polysaccharide monooxygenases (LMPOs) that cleave pectin”
t0“plant infection”
e1“P. infestans during infection”
e2“potato fields”
Claim · model-written summary
These monooxygenases were upregulated during P. infestans infection.
- Taxon
- potatoSolanum tuberosume1
- Interactor
- P. infestansPhytophthora infestanse0pathogen
- Gene
- LMPOse2
- Outcome
- upregulated in P. infestans during infectione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“are upregulated in P. infestans during infection.”
e1“potato fields”
e2“(LMPOs) that cleave pectin”
Claim · model-written summary
Silencing the monooxygenase gene inhibited P. infestans infection.
- Taxon
- potatoSolanum tuberosume1
- Treatment
- Silencing the relevant LMPO genee0
- Interactor
- P. infestansPhytophthora infestanse0pathogen
- Gene
- LMPO genee0
- Outcome
- P. infestans infectionse0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Silencing the relevant LMPO gene successfully inhibited P. infestans infections.”
e1“potato fields”
The same questions in other papers
loss of function · Phytophthora infestans · Solanum tuberosum (potato)Positive and negative results
15 papers in the same direction as this paper · 15 in the opposite direction
- positive
- negative
- no effect
27 papers more in this group
See all 31 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.