Abstract
Ophiorrhiza (Rubiaceae) is a critically endangered genus of Western Ghats. An investigation was carried out to explore the in vitro antioxidant and antibacterial activities of Ophiorrhiza pectinata Arn. andOphiorrhiza mungos L. To measure antioxidant activity, DPPH assay was performed and disc diffusion method was adopted for antibacterial activity. The IC50 values of DPPH assay recorded for O. pectinataand O. mungos were 78 g ml -1 and 62 g ml -1 , respectively. The crude extract of O. mungos and O. pectinata showed significant antibacterial activity against gram-positive and gram-negative bacteria. Thus, the study revealed that aqueous extracts of both Ophiorrhiza species had the potential to scavenge free radicals and to inhibit growth of pathogenic bacteria.
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Claims 0
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