BIOLOGICAL EVALUATION OF PROBIOTIC FERMENTED MILK (RAYEB) ON OBESE RATS

Abstract

Probiotics have been widely explored in food processing,production, research and disease prevention, therefore, the present studywas conducted to evaluate the biological evaluation of probioticfermented milk (Rayeb) on obese rats for 8 weeks. The rats (n=35) wereclassified into 5 groups, as follows: Group (1): fed on basal diet and keptas negative control group. While the rats (n= 28) were fed on high fatdiet for four weeks to induce obesity then were divided into four groups,group (2) was fed on high fat diet only and served as control positivegroup. Groups (3 and 4): obese rats were fed on high fat diet and weregiven orally 1 ml of fermented milk “Rayeb” and Vitamin D at 600IU/Kg BW respectively. Group (5): was fed on basal diet and was givenorally a mixture of (1 ml of Rayeb and Vitamin D at 600 IU/Kg BW).The results indicated that, the supplementation with fermentedmilk (Rayeb), vitamin D or their mixture significantly decreased(P<0.05) the final body weight compared to the positive control group by26.27%, 21.84%, 30.03%, respectively due to lowering the feed intakeand the feed efficiency ratio of the obese rats. Moreover, theconcentration of leptin hormone as well as the percent of peritoneal fatbad were significantly lowered (P<0.05) for all treated groups. It wasobserved that, the supplementation with the tested food materialsimproved the liver and kidney functions as well as lipid profile of the obese rats. It could be concluded that, fermented milk (Rayeb), vitamin Dor their mixture might be useful in weight reduction.

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