Paper · 2022 · Journal of Pharmaceutical Negative Results

Comparison of the therapeutic role of garlic extract and verapamil against gentamicin-induced nephrotoxicity in rats

Hmood Sh; Subhi; Siham Wade; et al.

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Abstract

Background: The aminoglycoside group, especially gentamicin, is the critical antibiotic in severe Gram-negative bacterial infections through its significant risk of nephrotoxicity. There are many protective factors for the kidneys, including blocking the flow of calcium to the damaged cells of the kidneys and reducing renal blood flow through the drug verapamil, In the same regard, garlic has been proven to be an antioxidant, a natural plant remedy for kidney protection.

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