Abstract
Understanding the management of the rice root-knot nematode Meloidogyne graminicola is an essential component of rice. The study aimed to investigate the extent to which the nematicidal actions of 2,1,3- benzothiadiazole, fluopyram, fluensulfone and carbofuran against the rice root-knot nematode, M. graminicola could be determined using in vitro, in vivo and in silico studies. Among the tested compounds, fluopyram demonstrated the highest juvenile mortality rate (91.26%) and binding affinity (-8.3 kcal/mol) to the seven selected target proteins of M. graminicola, driven by significant hydrophobic, alkyl and H-bonding interactions. Comparative binding affinities were recorded for fluensulfone (-6.9 kcal/mol), carbofuran (-6.4 kcal/mol), 2,1,3-benzothiadiazole (-5.0 kcal/mol) and untreated control. These findings have significant implications for agricultural practices, particularly in developing integrated pest management (IPM) strategies. The high efficacy of fluopyram, as evidenced by its biochemical ligand-target protein interactions, suggests its potential as a key component in IPM programs. By integrating nematicidal treatments with other control measures such as crop rotation, resistant rice varieties and biological control agents, sustainable management of M. graminicola can be achieved by reducing dependency on chemical pesticides. Furthermore, this study underscores the importance of using molecular insights to design targeted pest management solutions, paving the way for environmentally responsible and economically viable approaches to nematode control in rice cultivation.
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Claims 6
Claim · model-written summary
Fluopyram had the highest juvenile mortality rate, 91.26%.
- Taxon
- rice
Oryza sativat0 - Treatment
- fluopyrame0
- Interactor
- Meloidogyne graminicolaMeloidogyne graminicolae1pest
- Outcome
- juvenile mortality ratee0
- Direction
- higheste0
- Value
- 91.26%e0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“fluopyram demonstrated the highest juvenile mortality rate (91.26%)”
t0“rice root-knot nematode”
e1“rice root-knot nematode Meloidogyne graminicola”
Claim · model-written summary
Fluopyram had the highest binding affinity, -8.3 kcal/mol, to seven M. graminicola proteins.
- Taxon
- riceOryza sativat0
- Treatment
- fluopyrame0
- Interactor
- M. graminicolaMeloidogyne graminicolae0pest
- Outcome
- binding affinitye0
- Direction
- higheste0
- Value
- -8.3 kcal/mole0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“fluopyram demonstrated the highest juvenile mortality rate (91.26%) and binding affinity (-8.3 kcal/mol) to the seven selected target proteins of M. graminicola”
t0“rice root-knot nematode”
Claim · model-written summary
Fluensulfone binding affinity was -6.9 kcal/mol.
- Taxon
- riceOryza sativat0
- Treatment
- fluensulfonee0
- Interactor
- M. graminicolaMeloidogyne graminicolae2pest
- Outcome
- binding affinitiese1
- Value
- -6.9 kcal/mole0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“fluensulfone (-6.9 kcal/mol)”
t0“rice root-knot nematode”
e1“Comparative binding affinities were recorded for fluensulfone (-6.9 kcal/mol), carbofuran (-6.4 kcal/mol), 2,1,3-benzothiadiazole (-5.0 kcal/mol) and untreated control.”
e2“target proteins of M. graminicola”
Claim · model-written summary
Carbofuran binding affinity was -6.4 kcal/mol.
- Taxon
- riceOryza sativat0
- Treatment
- carbofurane0
- Outcome
- binding affinitiese1
- Value
- -6.4 kcal/mole0
Not reportedInteractor
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“carbofuran (-6.4 kcal/mol)”
t0“rice root-knot nematode”
e1“Comparative binding affinities were recorded for fluensulfone (-6.9 kcal/mol), carbofuran (-6.4 kcal/mol), 2,1,3-benzothiadiazole (-5.0 kcal/mol) and untreated control.”
Claim · model-written summary
Benzothiadiazole binding affinity was -5.0 kcal/mol.
- Taxon
- riceOryza sativat0
- Treatment
- 2,1,3-benzothiadiazolee0
- Outcome
- binding affinitiese1
- Value
- -5.0 kcal/mole0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“2,1,3-benzothiadiazole (-5.0 kcal/mol)”
t0“rice root-knot nematode”
e1“Comparative binding affinities were recorded for fluensulfone (-6.9 kcal/mol), carbofuran (-6.4 kcal/mol), 2,1,3-benzothiadiazole (-5.0 kcal/mol) and untreated control.”
Claim · model-written summary
The authors suggest fluopyram as a component of integrated pest management.
- Taxon
- riceOryza sativat0
- Treatment
- fluopyrame0
- Outcome
- key component in IPM programse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“fluopyram, as evidenced by its biochemical ligand-target protein interactions, suggests its potential as a key component in IPM programs”
t0“rice root-knot nematode”
The same questions in other papers
fluopyram · Meloidogyne graminicola · Oryza sativa (rice)Results agree
1 paper in the same direction as this paper
- positive
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.