Paper · 2025 · international journal of green and herbal chemistry

Usages of Phytochemicals: their Safety, Dosages and Regulatory Aspects

Raj Kumari; Meenakshi Sharma; A Kumar; et al.

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Abstract

Phytochemicals, bioactive compounds derived from plants, play a significant role in health maintenance and disease prevention.Their use spans nutraceuticals, traditional medicine and functional foods due to their antioxidant, anti-inflammatory and therapeutic properties.However, ensuring the safe use of phytochemicals requires thorough understanding of their toxicity, appropriate dosages and adherence to regulatory guidelines.Dosage determination is influenced by factors such as bioavailability, therapeutic index and synergistic combinations with other compounds, aiming to achieve an optimal balance between efficacy and safety.Regulatory frameworks vary globally, with organizations like the FDA, EMA and FSSAI enforcing standards on manufacturing practices, product labeling and claims to ensure consumer safety.This abstract emphasizes the critical need for rigorous safety evaluations, accurate dosage guidelines, and comprehensive regulations to support the safe and effective use of phytochemicals in healthcare.Phytochemicals, bioactive compounds derived from plants, hold significant therapeutic potential but must be used with caution due to concerns surrounding safety, Usages of

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