Paper · 2025 · Pest Management Science

Eco‐friendly diflufenican nanosuspension improved foliar dispersion, penetration, and contact herbicidal activity against broadleaf weeds by uniform deposition

Xuejian Cheng; Chengying Ding; Aiping Wang; et al.

5
claims
6
verbatim quotes
2
citations
2
research areas
—
Not open access

Abstract

BACKGROUND: Herbicides play an irreplaceable role in ensuring global food production and security. The low dispersion, non-uniform deposition, and negligible translocation of low water-soluble contact herbicides restrict the bioactivity. Therefore, there is an urgent need to develop novel, promising, and eco-friendly pesticide formulations to improve bioactivity and reduce the environmental input of herbicides. RESULTS: The diflufenican nanosuspension (NS) with satisfactory physical stability was prepared by wet media milling. The uniform deposition of diflufenican nanoparticles in NS on the surface of weed leaves improved the contact area with the target and enhanced the efficiency in penetrating the biological barrier. The indoor and field experiments showed that NS can exhibit comparable contact herbicidal activity against broadleaf weeds even with a 50% reduction in dosage compared to conventional pesticide formulations without negatively affecting the safety of wheat. The superior herbicidal activity of NS was due to its stronger ability to bind to the phytoene desaturase and prevent carotenoid biosynthesis, which further accelerated chlorophyll degradation. CONCLUSIONS: Our research represents an eco-friendly, low-cost, and scalable pathway for the efficient delivery of low water-soluble contact herbicides, which can provide practical support for reducing the environmental inputs and increasing the efficiency of contact herbicides. © 2025 Society of Chemical Industry.

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Claims 5

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The diflufenican nanosuspension showed comparable contact herbicidal activity against broadleaf weeds with a 50% dose reduction compared with conventional formulations.

Taxon
broadleaf weedse1
Treatment
NSe1
Outcome
contact herbicidal activitye1
Direction
comparablee1
Value
50% reduction in dosagee1
Comparator
conventional pesticide formulationse1
Setting
indoor and field experimentse1

Verbatim

e1

“The indoor and field experiments showed that NS can exhibit comparable contact herbicidal activity against broadleaf weeds even with a 50% reduction in dosage compared to conventional pesticide formulations without negatively affecting the safety of wheat”

✓ located verbatim in the source · abstract, characters 731–986 · show in text ↑
Intervention effectobservedoriginal resultno effectmeasured

Claim · model-written summary

The diflufenican nanosuspension did not negatively affect the safety of wheat.

Treatment
NSe1
Outcome
safety of wheate1
Direction
without negatively affectinge1

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e1

“The indoor and field experiments showed that NS can exhibit comparable contact herbicidal activity against broadleaf weeds even with a 50% reduction in dosage compared to conventional pesticide formulations without negatively affecting the safety of wheat”

✓ located verbatim in the source · abstract, characters 731–986 · show in text ↑
Mechanismauthor interpretationoriginal resultpositivemeasured

Claim · model-written summary

The superior herbicidal activity of the nanosuspension is attributed to stronger binding to phytoene desaturase, which prevents carotenoid biosynthesis and accelerates chlorophyll degradation.

Taxon
broadleaf weedse1
Gene
phytoene desaturasee3
Compound
carotenoide3
Outcome
superior herbicidal activitye3

Verbatim

e1

“The indoor and field experiments showed that NS can exhibit comparable contact herbicidal activity against broadleaf weeds even with a 50% reduction in dosage compared to conventional pesticide formulations without negatively affecting the safety of wheat”

✓ located verbatim in the source · abstract, characters 731–986 · show in text ↑
e3

“The superior herbicidal activity of NS was due to its stronger ability to bind to the phytoene desaturase and prevent carotenoid biosynthesis, which further accelerated chlorophyll degradation”

✓ located verbatim in the source · abstract, characters 988–1180 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The nanosuspension enhanced the efficiency of penetration of weed leaves through the biological barrier.

Taxon
weede2
Treatment
uniform deposition of diflufenican nanoparticles in NSe2
Outcome
efficiency in penetrating the biological barriere2
Direction
enhancede2

Not reportedComparator

Verbatim

e2

“The uniform deposition of diflufenican nanoparticles in NS on the surface of weed leaves improved the contact area with the target and enhanced the efficiency in penetrating the biological barrier”

✓ located verbatim in the source · abstract, characters 533–729 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The nanosuspension improved the contact area between weed leaves and the target.

Taxon
weede2
Treatment
uniform deposition of diflufenican nanoparticles in NSe2
Outcome
contact area with the targete2
Direction
improvede2

Not reportedComparator

Verbatim

e2

“The uniform deposition of diflufenican nanoparticles in NS on the surface of weed leaves improved the contact area with the target and enhanced the efficiency in penetrating the biological barrier”

✓ located verbatim in the source · abstract, characters 533–729 · show in text ↑

nanoparticle · organism · Triticum aestivum (wheat)Positive and negative results

8 papers: 4 positive, 4 negative or no effect

3 papers in the same direction as this paper · 4 in the opposite direction

  1. positive
  2. positive
  3. positive

4 papers more in this group

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Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.