Paper · 2026 · Zenodo (CERN European Organization for Nuclear Research)

MACROSCOPIC AND PHYSIO-CHEMICAL DESCRIPTION OF GHRITKUMARYĀDI AŚCHYOTANA

Shabnam Verma*1 (BAMS), Dr. Hardev Singh Thakur2 (BAMS, MS), Prof. Dr. Vijayant Bhardwaj3 (BAMS, MS)

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Abstract

Ghr̥itkumaryadi Aschyotana is an Ayurvedic ophthalmic preparation containing Ghritkumari (Aloe vera), Daruharidra (Berberis aristata), Madhu (Honey), and Glycerine, formulated to support ocular health in conditions involving inflammation and infection. The present study evaluates its macroscopic and physio-chemical parameters in accordance with ASU Pharmacopeial standards. Macroscopic analysis revealed a transparent liquid with a pleasant odour. Physio-chemical analysis demonstrated pH 6.08, loss on drying 96.37%, refractive index (R.I.) 1.336, specific gravity 1.020, and refractometer reading 2.95%. Thin Layer Chromatography confirmed the presence of Ghritkumari and Daruharidra with characteristic Rf values 0.29 and 0.53. These findings validate the quality, purity, and authenticity of Ghr̥itkumaryādi Aśchyotana and support its traditional therapeutic utility in ophthalmic disorders.

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