Claim · model-written summary
Microarray analysis of AT-induced cell death revealed a set of new H2O2-responsive genes highly regulated in a common fashion across types of programmed cell death.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae0 - Outcome
- a set of new H(2)O(2)-responsive genese1
Verbatim
e0“Arabidopsis thaliana”
e1“Microarray analysis with a DNA chip representing 21500 genes and subsequent comparison with other PCD-related expression studies revealed a set of new H(2)O(2)-responsive genes that were highly regulated in a common fashion during different types of PCD”
Title
Tsanko Gechev; Ivan Minkov; Jacques Hille IUBMB Life 2005. doi:10.1080/15216540500090793
Other claims from this paper (4)
- Intervention effect The catalase inhibitor aminotriazole reduced catalase activity in Arabidopsis thaliana.
- Intervention effect Aminotriazole caused endogenous accumulation of hydrogen peroxide that eventually triggered cell death in Arabidopsis.
- Observation The H2O2-responsive genes included an oxoglutarate-dependent dioxygenase, various oxidoreductases, the transcription factors Zat11, WRKY75 and NAM, and proteasomal components.
- Intervention effect Knockout lines of the oxoglutarate-dependent dioxygenase showed significantly reduced death symptoms and chlorophyll loss upon H2O2-induced cell death.