Claim · model-written summary
The authors propose that genes other than TOM1 participate in both TMV and CMV multiplication.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianat0 - Gene
- a gene(s) that is distinct from the TOM1 genee0
- Outcome
- TMV and CMV multiplicatione0
Verbatim
e0“These observations are compatible with a hypothetical model in which a gene(s) that is distinct from the TOM1 gene is involved in both TMV and CMV multiplication.”
t0“Arabidopsis thaliana”
Title
M Ishikawa; S Naito; T Ohno Journal of Virology 1993. doi:10.1128/jvi.67.9.5328-5338.1993
Other claims from this paper (10)
- Intervention effect The tom1 mutation affects amplification of TMV-related RNAs within a single cell.
- Intervention effect The proportion of TMV-positive protoplasts was about one-fifth to one-tenth as high in PD114 as in wild type.
- Intervention effect Positive-strand RNA and coat protein levels in TMV-positive PD114 cells were similar to or slightly lower than wild type.
- Intervention effect Positive-strand RNAs and coat protein accumulated more slowly in PD114 than wild type.
- Mechanism The parallel decline in coat protein and its mRNA suggests normal translation efficiency.
- Mechanism The observations support TOM1 encoding a host factor required for efficient TMV RNA amplification.
- Intervention effect CMV coinfection reduced TMV-related molecule accumulation in PD114 to approximately one-fifth of TMV alone.
- Intervention effect Wild-type cells showed no reduction in TMV-related accumulation with TMV and CMV together.
- Intervention effect Wild-type cells showed no reduction in TMV-related accumulation when TMV and turnip crinkle virus RNAs were combined.
- Intervention effect PD114 cells showed no reduction in TMV-related accumulation when TMV and turnip crinkle virus RNAs were combined.