Claim · model-written summary
A group of SGS3-like proteins acts redundantly in RdDM in Arabidopsis.
- Taxon
- Arabidopsis
Arabidopsise0 - Gene
- a group of SGS3-like proteinse0
- Outcome
- act redundantly in RNA-directed DNA methylatione0
Verbatim
e0“Here, we show that a group of SGS3-like proteins act redundantly in RNA-directed DNA methylation (RdDM) pathway in Arabidopsis”
Title
A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA methylation
Meng Xie; Guodong Ren; Pedro Costa-Nunes; et al. Nucleic Acids Research 2012. doi:10.1093/nar/gks034
Other claims from this paper (8)
- Association FDM1 and FDM2 expression is significantly correlated with known RdDM genes in Arabidopsis.
- Intervention effect The fdm1 and fdm2 double mutations significantly impaired DNA methylation at RdDM loci relative to the fdm1 or fdm2 single mutations.
- Intervention effect The fdm1 or fdm2 single mutations did not significantly impair DNA methylation at RdDM loci.
- Intervention effect The fdm1 and fdm2 double mutations released transcriptional gene silencing.
- Intervention effect The fdm1 and fdm2 double mutations dramatically reduced the abundance of siRNAs originated from high copy number repeats or transposons.
- Observation FDM1 binds dsRNAs with 5' overhangs.
- Observation IDN2 and FDM3, FDM4 and FDM5 have overlapping function with FDM1 in RdDM.
- Observation Five FDM proteins and IDN2 define a group of SGS3-like proteins that possess all four-signature motifs in Arabidopsis.