Claim · model-written summary
The Aspergillus neoniger extract had the highest antifungal effect, with an MIC of 3.75 ug/mL.
- Taxon
- Ficus carica
_(Ficus_carica)_-_Cagliari%2C_Italy_2024-03-26.jpg?width=60)
Ficus caricat0 - Interactor
- A. neoniger
Aspergillus neonigere0symbiont - Outcome
- antifungal effecte0
- Direction
- higheste0
- Value
- 3.75 µg mL −1e0
Verbatim
e0“highest antifungal effect observed for A. neoniger extract (MIC = 3.75 µg mL −1 )”
t0“endophytes of Ficus carica”
Title
Investigation of bioactivities of endophytes of Ficus carica L. Fam Moraceae
Randa Abdou; Mariam Mojally; Gouda H. Attia Bulletin of the National Research Centre/Bulletin of the National Research Center 2021. doi:10.1186/s42269-021-00505-1
Other claims from this paper (6)
- Observation The first three endophytes isolated from Ficus carica aerial parts were identified as Chaetomium globosum, Penicillium oxalicum and Alternaria alternata.
- Observation Two further endophytes isolated from Ficus carica were identified as Fusarium proliferatum and Aspergillus neoniger.
- Intervention effect Extracts of all endophytic strains had antiproliferative effects against HUVEC and K-562 cells with GI50 values of 4.75 to 13.75 ug/mL.
- Intervention effect Extracts of the endophytic strains were cytotoxic against HeLa cells with CC50 values of 8.25 to 18.75 ug/mL.
- Observation All endophyte strain extracts exerted antibacterial and antifungal activities.
- Mechanism The results are taken to support the assumption that endophytes of F. carica contribute to the plant reported antimicrobial and anticancer activities.