Claim · model-written summary
Viability of isolated wDi cells also decreased in response to the FANA ASO treatment.
- Treatment
- FANA ASO treatmente0
- Interactor
- wDie0symbiont
- Outcome
- Viability of isolated wDi cellse0
- Direction
- decreasede0
CitrusNot reportedComparator
Verbatim
e0“Viability of isolated wDi cells also decreased in response to the FANA ASO treatment.”
e1“Root infusions of a CLas-specific FANA ASO into infected Citrus trees”
Title
Antibacterial FANA oligonucleotides as a novel approach for managing the Huanglongbing pathosystem
Andrés F. Sandoval-Mojica; Wayne B. Hunter; Veenu Aishwarya; et al. Scientific Reports 2021. doi:10.1038/s41598-021-82425-8
Other claims from this paper (5)
- Method / resource FANA ASO are able to penetrate insect cells without the use of a delivery agent.
- Intervention effect Expression of an essential gene in the D. citri endosymbiont, Wolbachia (wDi), significantly decreased by 30% following incubation with a wDi-specific FANA ASO.
- Intervention effect Delivery of a CLas-specific FANA ASO to infected adult D. citri in feeding assays resulted in significant silencing of a CLas essential gene.
- Intervention effect CLas relative density and transmission were significantly lower among D. citri fed FANA ASO in diet compared to untreated insects.
- Intervention effect Root infusions of a CLas-specific FANA ASO into infected Citrus trees significantly reduced CLas titer during a 30-day trial.