Claim · model-written summary
DPH2 localizes to the cytosol
- Taxon
- Arabidopsis
Arabidopsist0 - Gene
- DPH2e0
- Outcome
- localizes to the cytosole0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“Here, we identify Arabidopsis (Arabidopsis thaliana) DPH2 and show that it is required for diphthamide biosynthesis, localizes to the cytosol”
t0“Arabidopsis”
Title
Hongliang Zhang; Nadežda Janina; Koray Ütkür; et al. PLANT PHYSIOLOGY 2025. doi:10.1093/plphys/kiaf128
Other claims from this paper (11)
- Observation DPH2 is required for diphthamide biosynthesis
- Observation DPH2 physically interacts with AtDPH1
- Observation dph2 mutants have shorter primary roots than wild type
- Observation dph2 mutants have smaller rosettes than wild type
- Observation dph2 mutants have increased ribosomal -1 frameshifting error rates
- Observation dph2 mutants have attenuated TOR kinase activity
- Observation dph1 and dph2 mutants are hypersensitive to elevated light intensities
- Observation dph1 and dph2 mutants are hypersensitive to oxidative stress
- Observation Wild-type seedlings accumulate diphthamide-unmodified eEF2 under oxidative stress
- Observation Both mutants share deregulation of 1,186 transcripts associated with environmental and hormone responses
- Observation AtDPH1 and AtDPH2 do not complement corresponding yeast mutants