Claim · model-written summary
The nine-amino acid region was highly variable among plant CAX-like transporters.
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Verbatim
e0“This nine-amino acid region is highly variable among the plant CAX-like transporters”
Title
Structural Determinants of Ca2+ Transport in the Arabidopsis H+/Ca2+Antiporter CAX1
Toshiro Shigaki; Ning-hui Cheng; Jon K. Pittman; et al. Journal of Biological Chemistry 2001. doi:10.1074/jbc.m106637200
Other claims from this paper (9)
- Observation CAX1 had higher Ca(2+) transport capacity than CAX2.
- Observation CAX3 is 77% identical to CAX1.
- Observation CAX3 localized to the yeast vacuole but did not suppress the transport-defective mutants.
- Intervention effect Insertion of a nine-amino acid CAX1 region enabled CAX3 to suppress yeast transport mutants.
- Observation CAX3-9 had 36% of CAX1 H(+)/Ca(2+) exchange activity.
- Observation CAX3-9 and CAX1 differed in transport of other ions.
- Intervention effect Putting the CAX1 region into CAX2 doubled yeast vacuolar calcium transport.
- Intervention effect That CAX1 region did not appear to alter CAX2 transport of other ions.
- Mechanism The authors infer that this region participates in CAX-mediated calcium specificity.