Claim · model-written summary
Foc4-305 stabilized Ma-PRP proteins in vivo.
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingValueQualifier
Verbatim
t0“Targets a Proline-Rich Protein in Banana”
e5“Foc4-305 stabilized Ma-PRP proteins in vivo”
Title
Liqian You; Jiahui Wu; Wenjing Chen; et al. Journal of Agricultural and Food Chemistry 2026. doi:10.1021/acs.jafc.5c15723
Other claims from this paper (10)
- Intervention effect Deletion of Foc4-305 diminished pathogenicity toward banana plants.
- Intervention effect Deletion of Foc4-305 impaired fungal growth.
- Intervention effect Deletion of Foc4-305 heightened sensitivity to oxidative stresses and cell wall disruptors.
- Observation Foc4-305 localized primarily in the nuclei and cytoplasm of Nicotiana benthamiana cells.
- Observation Foc4-305 could inhibit BAX-triggered cell death in Nicotiana benthamiana.
- Observation Foc4-305 interacts with the banana proline-rich protein Ma-PRP, as confirmed by yeast two-hybrid, BiFC and co-immunoprecipitation.
- Intervention effect Virus-induced gene silencing of Ma-PRP enhanced banana resistance to wilt disease.
- Observation RNA-seq revealed differentially expressed genes between wild-type Foc4 and Foc4-305 knockout mutants.
- Observation GO and KEGG analyses associated the differentially expressed genes with reproduction, DNA repair and amino acid metabolism.
- Mechanism Foc4-305 enhances Foc4 virulence on banana by modulating growth, stress responses and host immunity.