Claim · model-written summary
Line 764 (mSEB) significantly altered native soybean gene expression, with more than 3000 genes up- or downregulated relative to wild type seeds.
- Taxon
- soybean
Glycine maxe1 - Material
- 764e1
- Organ / stage
- seedse3
- Treatment
- expressing a mutant, nontoxic form of a staphylococcal subunit vaccine proteine2
- Outcome
- gene expressione1
- Value
- more than 3000 genese1
- Comparator
- wild type seedse3
Not reportedGeneCompoundInteractorInteractor roleSecond interactorSecond interactor roleSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Native soybean gene expression was significantly altered in line 764 (mSEB) with more than 3000 genes being upregulated or downregulated”
e2“764, expressing a mutant, nontoxic form of a staphylococcal subunit vaccine protein (mSEB)”
e3“compared with wild type seeds”
Title
Kevin C. Lambirth; Adam M. Whaley; Ivory C. Blakley; et al. BMC Biotechnology 2015. doi:10.1186/s12896-015-0207-z
Other claims from this paper (8)
- Observation Line ST77 (hTG) showed no significant gene ontology enrichment.
- Observation Line ST77 (hTG) had significantly fewer differences from wild type, with 52 differentially expressed genes.
- Observation Line ST111 (hMBP) had significantly fewer differences from wild type, with 307 differentially expressed genes.
- Observation Only a few genes involved in photosynthesis and thylakoid functions were downregulated in line ST111.
- Observation Genes annotated to endopeptidase inhibitors and protein synthesis were upregulated in line 764.
- Observation Genes annotated to the nuclear pore and to protein transport were suppressed in line 764.
- Observation Transgenic soybean plants and seeds appeared phenotypically similar to non-transgenic controls.
- Association No correlation was found between recombinant protein expression level and the quantity of differentially expressed genes.