Claim · model-written summary
None of the cladode extracts induced genotoxic effects in the comet assay compared with the negative control.
- Treatment
- extractse4
- Outcome
- genotoxic effectse4
- Direction
- none of the extracts inducede4
- Comparator
- negative controle4
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
t0“Opuntia Species”
e4“Importantly, none of the extracts induced genotoxic effects compared to the negative control, while all differed significantly from the oxidative damage induced by hydrogen peroxide”
Title
Abderrahmane Hadini; Mounsef Neffa; Sanae Baddaoui; et al. Antioxidants 2026. doi:10.3390/antiox15040416
Other claims from this paper (8)
- Observation O. ficus-indica had the highest total phenolic and flavonoid contents among the three Opuntia species.
- Observation O. ficus-indica had the strongest radical scavenging and reducing capacities among the three Opuntia species.
- Observation O. stricta was particularly rich in ascorbic acid.
- Observation O. stricta had the highest total antioxidant capacity among the three Opuntia species.
- Observation Metabolomic profiling of the cladode extracts found a predominance of phenolic acids and flavonoids.
- Observation Piscidic acid was a major constituent of the cladode extracts.
- Observation Isorhamnetin derivatives and organic acids were also detected in the cladode extracts.
- Intervention effect The cladode extracts differed significantly from the oxidative damage induced by hydrogen peroxide.