Claim · model-written summary
CG, CHG and CHH methylation increased at sites of upregulated R-loops.
- Taxon
- Brachypodium
Brachypodiumt0 - Outcome
- CG, CHG, and CHH DNA methylation levelse0
- Direction
- increasese0
- Qualifier
- sites of upregulatede0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“global increases and decreases in CG, CHG, and CHH DNA methylation levels at sites of upregulated and downregulated R-loops, respectively”
t0“Brachypodium”
Title
Kaibiao Zhang; Lisha Shen; Yishuang Sun; et al. The Plant Journal 2026. doi:10.1111/tpj.70957
Other claims from this paper (6)
- Observation R-loops were highly conserved in syntenic regions between diploid and allotetraploid genomes.
- Observation R-loop formation was strongly sequence dependent and persisted in rearranged regions after polyploidization.
- Association Sequence dependent R-loops were largely unaffected by RNA abundance and chromatin accessibility.
- Observation Sequence dependent R-loops were associated with small sequence variants.
- Observation CG, CHG and CHH methylation decreased at sites of downregulated R-loops.
- Observation Fluctuations in R-loop abundance affected both sense and antisense DNA strands.