Claim · model-written summary
The replication strategy lets the virus separate minus- and plus-strand synthesis in time.
- Taxon
- plantsViridiplantaee0
- Outcome
- separate minus- and plus-strand syntheses in timee6
- Qualifier
- replication strategye6
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Verbatim
e0“Replication of plus-strand RNA [(+)RNA] viruses of plants”
e6“this replication strategy allows TBSV to separate minus- and plus-strand syntheses in time and regulate asymmetrical RNA replication that leads to abundant (+)RNA progeny”
Title
Template Role of Double-Stranded RNA in Tombusvirus Replication
Nikolay Kovalev; Judit Pogany; Peter D. Nagy Journal of Virology 2014. doi:10.1128/jvi.03842-13
Other claims from this paper (5)
- Observation Replication of Tomato bushy stunt virus leads to the formation of double-stranded RNA.
- Observation No naked (-)RNA templates are present during Tomato bushy stunt virus replication.
- Observation dsRNA appeared rapidly, earlier than the bulk production of new (+)RNAs.
- Mechanism Tomato bushy stunt virus replication involves dsRNA templates in strand displacement reactions.
- Mechanism dsRNA is used as a template for (+)RNA synthesis, facilitated by recruited host DEAD box helicases and the viral p33 protein.