Claim · model-written summary
Neocentromeres are mobilized on microtubules by minus end-directed motor proteins.
Zea maysNot reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In maize, neocentromeres are induced by a gene or genes on Abnormal chromosome 10 (Ab10) which causes heterochromatic knobs to move poleward at meiotic anaphase”
e7“We argue that neocentromeres are mobilized on microtubules by the activity of minus end-directed motor proteins”
Title
Neocentromere-mediated Chromosome Movement in Maize
Hong-Guo Yu; Evelyn N. Hiatt; Annette Chan; et al. The Journal of Cell Biology 1997. doi:10.1083/jcb.139.4.831
Other claims from this paper (8)
- Observation Neocentromeres are active from prometaphase through anaphase in maize meiosis.
- Observation Normal chromosomes move on the spindle at an average rate of 0.79 micron/min during mid-anaphase.
- Intervention effect The presence of Ab10 does not affect the rate of normal chromosome movement.
- Intervention effect Ab10 propels neocentromeres poleward at rates as high as 1.4 micron/min.
- Intervention effect Kinetochore-mediated chromosome movement is only marginally affected by a linked neocentromere.
- Observation Unlike kinetochores, neocentromeres associate laterally with microtubules.
- Observation Neocentromere movement is correlated with knob size.
- Mechanism Microtubule depolymerization is not required for neocentromere motility.