Claim · model-written summary
Mutation of EXO70E1, EXO70E2 or SCD1 reduced secretion of TET8-, PEN1- and PATL1-marked EVs in Arabidopsis.
- Taxon
- Arabidopsis
Arabidopsise0 - Treatment
- Mutation of EXO70E1, EXO70E2 or STOMATAL CYTOKINESIS DEFECTIVE1e1
- Gene
- EXO70E1, EXO70E2 or STOMATAL CYTOKINESIS DEFECTIVE1e1
- Outcome
- secretion of EVse1
- Direction
- reducede1
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Arabidopsis (Arabidopsis thaliana)”
e1“Mutation of EXO70E1, EXO70E2 or STOMATAL CYTOKINESIS DEFECTIVE1 (SCD1; a GTP-exchange factor for RabE GTPases) reduced secretion of EVs marked by TETRASPANIN8 (TET8), PENETRATION1 (PEN1), and PATELLIN1 (PATL1)”
Title
Molecular insights into the production of extracellular vesicles by plants
Benjamin L Koch; Dillon Gardner; Hannah Smith; et al. PLANT PHYSIOLOGY 2026. doi:10.1093/plphys/kiag011
Other claims from this paper (7)
- Mechanism Proximity labeling, co-immunoprecipitation and fluorescence microscopy in Nicotiana benthamiana indicated a general role of EXO70 proteins in EV secretion.
- Mechanism Proximity labeling, co-immunoprecipitation and fluorescence microscopy in Nicotiana benthamiana indicated a general role of RIN4 in EV secretion.
- Intervention effect Mutation of RIN4 reduced levels of TET8+ and PEN1+ EVs in Arabidopsis.
- Intervention effect Mutation of RIN4 did not reduce levels of PATL+ EVs in Arabidopsis.
- Intervention effect Mutation of the small GTPase gene RABA2a specifically affected PEN1+ EV secretion in Arabidopsis.
- Intervention effect Mutations in ATG5 and VAP27 specifically affected TET8+ EV secretion in Arabidopsis.
- Association exo70 family mutants were more susceptible to infection with the fungal pathogen Colletotrichum higginsianum.