Claim · model-written summary
Stpm1 mutants had less pronounced disease symptoms and reduced lesion area than wild type after P. infestans inoculation.
- Taxon
- potato
Solanum tuberosumt0 - Treatment
- stpm1 mutantse0
- Outcome
- disease symptom and reduced lesion areae0
- Direction
- reducede0
- Comparator
- wild-type plantse0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the stpm1 mutants exhibited less pronounced disease symptom and reduced lesion area compared with the wild-type plants”
t0“potato”
Title
Weishuai Bi; Jing Liu; Yuanyuan Li; et al. Plant Biotechnology Journal 2023. doi:10.1111/pbi.14175
Other claims from this paper (19)
- Observation StPM1 was identified as a potato susceptibility factor involved in response to P. infestans.
- Observation P. infestans infection downregulated StPM1 expression.
- Observation Two homozygous StPM1-edited lines carried 1 bp and 3 bp deletions with frameshifts.
- Intervention effect Stpm1 mutants had elevated expression of four defence-related genes after infection.
- Intervention effect StPM1-edited potato plants had normal growth and development versus wild type.
- Intervention effect StPM1 overexpression increased susceptibility to P. infestans in potato.
- Intervention effect StPM1 overexpression increased susceptibility to P. capsici in N. benthamiana.
- Intervention effect StPM1 overexpression reduced induction of defence genes.
- Observation StPM1 localized to the plasma membrane in N. benthamiana leaves.
- Association StPM1 associated with NbRbohC in N. benthamiana.
- Association Co-immunoprecipitation and split-luciferase assays supported association of StPM1 and StRbohC.
- Intervention effect StPM1 coexpression significantly reduced StRbohC protein accumulation in N. benthamiana.
- Intervention effect Concanamycin A increased StRbohC accumulation.
- Intervention effect Concanamycin A blocked StPM1-induced StRbohC degradation.
- Intervention effect StPM1 overexpression inhibited chitin-induced ROS production and Avr3a/R3a-induced cell death.
- Intervention effect NbRbohC silencing diminished chitin-induced ROS production.
- Intervention effect NbRbohC silencing reduced resistance to P. capsici and P. infestans colonization.
- Observation Phylogenetic analysis found StPM1 conserved across monocots and dicots.
- Recommendation The authors suggest StPM1 modification as a candidate for improving crop disease resistance without growth penalty.