Claim · model-written summary
Wild-type AvrM14 reduced M1-triggered hypersensitive cell death relative to inactive AvrM14.
- Taxon
- flax
Linum usitatissimume0 - Treatment
- expression of wild-type AvrM14e0
- Gene
- M1e0
- Outcome
- hypersensitive cell-death responsee0
- Direction
- reducede0
- Comparator
- catalytically dead versione0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In planta expression of wild-type AvrM14, but not the catalytically dead version, suppressed immune-related reactive oxygen species production, altered the abundance of some circadian-rhythm-associated mRNA transcripts and reduced the hypersensitive cell-death response triggered by the flax disease resistance protein M1”
Title
A rust‐fungus Nudix hydrolase effector decaps mRNAin vitro and interferes with plant immune pathways
Carl L. McCombe; Ann‐Maree Catanzariti; Julian R. Greenwood; et al. New Phytologist 2023. doi:10.1111/nph.18727
Other claims from this paper (6)
- Observation AvrM14 selectively removed protective 5′ caps from mRNA in vitro.
- Mechanism AvrM14 homodimerization promoted biologically relevant mRNA cap cleavage in vitro.
- Observation Related Melampsora effectors retained mRNA cap cleavage activity.
- Intervention effect Wild-type AvrM14 expression in plants suppressed immune-related reactive oxygen species relative to catalytically dead AvrM14.
- Intervention effect Wild-type AvrM14 expression changed the abundance of circadian-rhythm-associated transcripts relative to inactive AvrM14.
- Mechanism The authors infer that fungal Nudix effectors with mRNA-decapping activity can interfere with plant immunity.