Claim · model-written summary
A plant VP1 expression vector was successfully constructed.
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Verbatim
e0“Experimental results showed that the plant expression vector was successfully constructed.”
e1“The plant constitutive expression vector pBin438/VP1 for VP1 gene of foot-and-mouth disease virus strain O/ China/99 was constructed.”
Title
Li Pan; Yong-Guang Zhang; Yong-Lu Wang; et al. PubMed 2006
Other claims from this paper (8)
- Method / resource Sixty resistant transformed tomato lines were obtained after selection.
- Observation Integration and transcription of VP1 in transformed tomato plants were confirmed.
- Observation About 40% of transformed plants expressed the recombinant protein.
- Observation Plant-expressed FMDV VP1 was specifically recognized by polyclonal antibodies against FMDV.
- Observation Guinea pig antibody titers reached 1:64 twenty-one days after the third inoculation.
- Observation Protection against FMDV challenge was 80% in one immunized guinea pig group.
- Observation Protection against FMDV challenge was 40% in the other immunized guinea pig group.
- Observation The authors concluded that transgenic tomato expression products were immunogenic and could induce specific FMDV antibodies in guinea pigs.