Claim · model-written summary
Compound 5z exerts antiviral effects by specifically binding the TMV coat protein.
- Taxon
- Tobacco mosaic virus
Tobacco mosaic viruse0 - Gene
- TMV coat proteine6
- Outcome
- antiviral effectse6
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tobacco mosaic virus (TMV) is one of the most destructive plant pathogens”
e6“5z exerts its multi‐target antiviral effects by specifically binding to the TMV coat protein”
Title
Synthesis, antiviral activity and mechanistic insights into cytidine derivatives
Rui Wang; Yueling Qin; Ming Chen; et al. Pest Management Science 2026. doi:10.1002/ps.70728
Other claims from this paper (8)
- Intervention effect Compound 5z exhibited excellent protective and curative effects against TMV.
- Method / resource Compound 5z had an EC50 of 191.84 μg mL −1 against TMV.
- Intervention effect Compound 5z outperformed the commercial agent ningnanmycin in EC50.
- Intervention effect Compound 5z outperformed the commercial agent ribavirin in EC50.
- Intervention effect Compound 5z triggered the plant defense enzyme system.
- Intervention effect Compound 5z boosted photosynthetic efficiency.
- Recommendation The authors conclude that compound 5z shows strong promise as a novel antiviral agent.
- Observation Structure-activity relationships were established for the cytidine derivatives.