Claim · model-written summary
Maize microtubules had an additional low-affinity site 12 dimers apart.
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionQualifier
Verbatim
t0“plant tubulin”
e0“an additional low-affinity site also 12 dimers apart that may be homologous to the mammalian tau binding site”
Title
J D Hugdahl; C L Bokros; V R Hanesworth; et al. The Plant Cell 1993. doi:10.1105/tpc.5.9.1063
Other claims from this paper (7)
- Observation MAP2 bound taxol-stabilized maize microtubules, saturating at one MAP2 per five to six tubulin dimers.
- Observation Maize microtubules had a high-affinity MAP2 site 12 dimers apart.
- Intervention effect MAP2 corrected in vitro folding errors in taxol-stabilized maize microtubules.
- Intervention effect MAP2 reduced the maize tubulin polymerization critical concentration eightfold, from 8.3 to 1.0 microM.
- Observation MAP2 dissociated more readily from maize than mammalian microtubules.
- Intervention effect MAP2 induced stable aberrant helical ribbon polymers of maize tubulin.
- Mechanism The authors infer partially specific, low-fidelity MAP2 binding to maize tubulin.