Claim · model-written summary
The Osrdr1 mutant showed 1,175 differentially expressed genes compared with WT in shoot tips.
- Taxon
- rice
Oryza sativat0 - Material
- Osrdr1e1
- Treatment
- loss-of-function mutante0
- Gene
- OsRDR1e0
- Outcome
- differentially expressed genese1
- Value
- 1,175e1
- Comparator
- WTe1
Not reportedCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Mutation of the RDR1 gene caused genome-wide changes in gene expression, regional variation in small RNA clusters and localized alteration in DNA methylation in rice”
e0“We characterized a loss-of-function mutant (Osrdr1) of the OsRDR1 gene in rice (Oryza sativa L.)”
e1“Microarray analysis identified 1,175 differentially expressed genes (5.2% of all expressed genes in the shoot-tip tissue of rice) between Osrdr1 and WT, of which 896 and 279 genes were up- and down-regulated, respectively, in Osrdr1”
Title
Ningning Wang; Di Zhang; Zhenhui Wang; et al. BMC Plant Biology 2014. doi:10.1186/1471-2229-14-177
Other claims from this paper (10)
- Intervention effect In the Osrdr1 mutant, 896 genes were up-regulated relative to WT.
- Intervention effect In the Osrdr1 mutant, 279 genes were down-regulated relative to WT.
- Observation smRNA sequencing revealed regional alterations in smRNA clusters across the rice genome.
- Association Some regions with altered smRNA clusters were associated with changes in DNA methylation.
- Observation Several miRNAs showed altered expression in the Osrdr1 mutant.
- Association Altered miRNA expression was associated with altered expression of predicted miRNA target genes.
- Intervention effect The Osrdr1 mutant showed no phenotypic difference from WT under normal conditions.
- Observation Ephemeral phenotypic fluctuations occurred in rice under some abiotic stress conditions.
- Mechanism OsRDR1 appears to regulate a substantial number of endogenous genes through smRNA-mediated pathways involving DNA methylation.
- Mechanism OsRDR1 appears to participate in the abiotic stress response of rice.