Claim · model-written summary
In vivo, compound C8 gave better protective efficacy (78.3%) than carbendazim at 200 μg/mL.
- Taxon
- rape
_Brassica_napus_-_Habit.jpg?width=60)
Brassica napuse5 - Treatment
- compound C8e2
- Outcome
- protective efficacye2
- Direction
- bettere2
- Value
- 78.3%e2
- Qualifier
- 200 μg/mLe2
- Comparator
- carbendazime2
- Setting
- in vivo teste2
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor role
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
_Brassica_napus_-_Habit.jpg?width=500)
Verbatim
e2“A further in vivo test confirmed that compound C8 possessed better protective efficacy (78.3%) than carbendazim (58.8%) at 200 μg/mL”
e5“In field trials, compound C8 provided significantly better control efficacy against rape sclerotinia stem rot (64.9%) than carbendazim (45.5%) at 750 g a.i./ha”
Title
Jinchao Shi; Panpan Yin; Xuyang Zhang; et al. Journal of Agricultural and Food Chemistry 2026. doi:10.1021/acs.jafc.5c11815
Other claims from this paper (10)
- Intervention effect Compound C3 had an EC50 of 0.479 μg/mL against S. sclerotiorum, more potent than carbendazim (0.586 μg/mL).
- Intervention effect Compound C7 had an EC50 of 0.476 μg/mL against S. sclerotiorum, more potent than carbendazim (0.586 μg/mL).
- Intervention effect Compound C8 had an EC50 of 0.240 μg/mL against S. sclerotiorum, more potent than carbendazim (0.586 μg/mL).
- Intervention effect Compound C11 had an EC50 of 0.390 μg/mL against S. sclerotiorum, more potent than carbendazim (0.586 μg/mL).
- Observation Most of the ternary thione/thioether derivatives showed excellent in vitro antifungal activity against Sclerotinia sclerotiorum and Rhizoctonia cerealis.
- Mechanism The 3D-QSAR model indicates that steric effects play a dominant role in the antifungal activity.
- Observation Compound C8 is phloem-mobile.
- Observation Compound C8 rapidly translocates to roots.
- Observation Compound C8 strongly inhibits sclerotial formation of Sclerotinia sclerotiorum.
- Intervention effect In field trials, compound C8 gave significantly better control efficacy (64.9%) against rape sclerotinia stem rot than carbendazim (45.5%) at 750 g a.i./ha.