Claim · model-written summary
About 15% of the inferred deleterious variants in diploid potato occur at synonymous sites.
- Taxon
- potato
Solanum tuberosume0 - Outcome
- deleterious variantse0
- Value
- 15%e0
- Qualifier
- synonymous sitese0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Based on a diploid potato diversity panel, we infer 367,499 deleterious variants, of which 50% occur at non-coding and 15% at synonymous sites”
Title
Phylogenomic discovery of deleterious mutations facilitates hybrid potato breeding
Yaoyao Wu; Dawei Li; Yong Hu; et al. Cell 2023. doi:10.1016/j.cell.2023.04.008
Other claims from this paper (5)
- Observation A whole-genome phylogeny of Solanaceae reveals highly constrained sites comprising about 2.4% of the genome.
- Observation Based on a diploid potato diversity panel, 367,499 deleterious variants were inferred.
- Observation About 50% of the inferred deleterious variants in diploid potato occur at non-coding sites.
- Observation Diploid potato lines with relatively high homozygous deleterious burden can be better starting material for inbred-line development despite less vigorous growth.
- Intervention effect Including inferred deleterious mutations increases genomic-prediction accuracy for yield by 24.7% in potato.