Claim · model-written summary
N-terminal domain mutants localized normally
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianat0 - Treatment
- N-terminal domain mutantse4
- Outcome
- localized normallye4
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“in Arabidopsis thaliana”
e4“N-terminal domain mutants localized normally but failed to complement the hma2,hma4 phenotypes”
Title
Chong Kum Edwin Wong; Renée S. Jarvis; Sarah M. Sherson; et al. New Phytologist 2008. doi:10.1111/j.1469-8137.2008.02637.x
Other claims from this paper (7)
- Intervention effect A deletion lacking the C-terminal 244 amino acids of HMA2 rescued most Zn-deficiency phenotypes of hma2,hma4 plants
- Intervention effect The 244-amino-acid C-terminal deletion did not rescue embryo or seed development
- Intervention effect Root-to-shoot Cd translocation was fully rescued by the C-terminal 244-amino-acid deletion
- Intervention effect The GFP-tagged HMA2 derivative was partially mis-localized in root pericycle cells
- Intervention effect Deletions lacking the C-terminal 121 and 21 amino acids rescued all phenotypes and localized normally
- Intervention effect N-terminal domain mutants failed to complement the hma2,hma4 phenotypes
- Mechanism The N-terminal domain of HMA2 is essential for function in planta