Claim · model-written summary
The potency of Zanthoxylum chalybeum extracts significantly differed from that of albendazole.
- Taxon
- Zanthoxylum chalybeum
Zanthoxylum chalybeume0 - Treatment
- plants extractse4
- Outcome
- potencye4
- Comparator
- albendazolee4
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“In vitro studies were conducted to determine the anthelmintic activity and phytochemical compounds of Zanthoxylum chalybeum”
e4“The potency of the plants extracts and albendazole significantly differed (P = 0.001)”
Title
S. Nalule African Journal of Pharmacy and Pharmacology 2013. doi:10.5897/ajpp2013.3664
Other claims from this paper (9)
- Intervention effect The aqueous extract of Zanthoxylum chalybeum inhibited 100% of Ascaris suum worm motility 48 h post exposure, compared with the negative control.
- Intervention effect The ethanolic extract of Zanthoxylum chalybeum inhibited 93% of Ascaris suum worm motility 48 h post exposure, compared with the negative control.
- Observation The ED50 of the ethanolic extract of Zanthoxylum chalybeum was 30.85 mg/ml.
- Observation The ED50 of the aqueous extract of Zanthoxylum chalybeum was 6.28 mg/ml.
- Intervention effect Zanthoxylum chalybeum extracts inhibited motility dose-dependently, with significant differences between dose levels compared with the negative control.
- Observation Zanthoxylum chalybeum extracts contained tannins, saponins and flavonoids.
- Observation Zanthoxylum chalybeum extracts contained alkaloids, reducing sugars and coumarin derivatives.
- Observation Zanthoxylum chalybeum extracts contained anthracenones and anthocyanins.
- Observation Thin layer chromatography of Zanthoxylum chalybeum extracts indicated polyphenols and sapogenins.