Abstract
The onset of flowering, the change from vegetative to reproductive development, is a major life history transition in flowering plants. Recent work suggests that mutations in cis-regulatory mutations should play critical roles in the evolution of this (as well as other) important adaptive traits, but thus far there has been little evidence that directly links regulatory mutations to evolutionary change at the species level. While several genes have previously been shown to affect natural variation in flowering time in Arabidopsis thaliana, most either show protein-coding changes and/or are found at low frequency (<5%). Here we identify and characterize natural variation in the cis-regulatory sequence in the transcription factor CONSTANS that underlies flowering time diversity in Arabidopsis. Mutation in this regulatory motif evolved recently and has spread to high frequency in Arabidopsis natural accessions, suggesting a role for these cis-regulatory changes in adaptive variation of flowering time.
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Claims 4
Claim · model-written summary
Natural cis-regulatory variation in CONSTANS underlies flowering time diversity in Arabidopsis.
- Taxon
- Arabidopsis
Arabidopsise0 - Gene
- CONSTANSe0
- Outcome
- flowering time diversitye0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“natural variation in the cis-regulatory sequence in the transcription factor CONSTANS that underlies flowering time diversity in Arabidopsis”
Claim · model-written summary
The regulatory motif mutation evolved recently in Arabidopsis.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- Mutation in this regulatory motif evolved recentlye0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Mutation in this regulatory motif evolved recently”
t0“Arabidopsis”
Claim · model-written summary
The regulatory motif mutation spread to high frequency in Arabidopsis natural accessions.
- Taxon
- ArabidopsisArabidopsise0
- Outcome
- frequency in Arabidopsis natural accessionse0
- Direction
- highe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“has spread to high frequency in Arabidopsis natural accessions”
Claim · model-written summary
The authors suggest that CONSTANS cis-regulatory changes may contribute to adaptive flowering time variation.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- adaptive variation of flowering timee0
- Qualifier
- these cis-regulatory changese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“suggesting a role for these cis-regulatory changes in adaptive variation of flowering time”
t0“Arabidopsis”