Paper · 2006 · Planta Medica

Cytotoxic Compounds of Schizolaena hystrix from the Madagascar Rainforest

Brian Murphy; Shugeng Cao; Andrew Norris; et al.

3
claims
6
verbatim quotes
11
citations
1
research areas
—
Not open access

Abstract

Bioassay-guided fractionation of a crude ethanol extract from a Madagascar collection of Schizolaena hystrix afforded the two new long-chain compounds, 3 S-acetoxyeicosanoic acid ethyl ester ( 1) and 3 S-acetoxydoeicosanoic acid ( 2), and the known long-chain compound 3 S-acetoxyeicosanoic acid ( 3). In addition, the long-chain alcohol 1-hydroxydodecan-2-one ( 7), as well as the new flavonoid schizolaenone C ( 4) and the two known flavonoids diplacol ( 5) and 3'-prenylnaringenin ( 6) were isolated from a methanol extract of the same plant. Isolation and structure elucidation of the novel compounds and the cytotoxicities of all the isolates are reported.

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Claims 3

Observationobservedoriginal resultmeasured

Claim · model-written summary

Bioassay-guided fractionation of an ethanol extract of Schizolaena hystrix yielded two new long-chain compounds and one known long-chain compound.

Taxon
Schizolaena hystrixSchizolaena hystrixe0
Outcome
long-chain compoundse1

Verbatim

e0

“Bioassay-guided fractionation of a crude ethanol extract from a Madagascar collection of Schizolaena hystrix”

✓ located verbatim in the source · abstract, characters 0–108 · show in text ↑
e1

“afforded the two new long-chain compounds, 3 S-acetoxyeicosanoic acid ethyl ester ( 1) and 3 S-acetoxydoeicosanoic acid ( 2), and the known long-chain compound 3 S-acetoxyeicosanoic acid ( 3)”

✓ located verbatim in the source · abstract, characters 109–300 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The long-chain alcohol 1-hydroxydodecan-2-one was isolated from a methanol extract of Schizolaena hystrix.

Taxon
Schizolaena hystrixSchizolaena hystrixe0
Outcome
long-chain alcohol 1-hydroxydodecan-2-onee2
Qualifier
isolated from a methanol extracte2

Verbatim

e0

“Bioassay-guided fractionation of a crude ethanol extract from a Madagascar collection of Schizolaena hystrix”

✓ located verbatim in the source · abstract, characters 0–108 · show in text ↑
e2

“the long-chain alcohol 1-hydroxydodecan-2-one ( 7), as well as the new flavonoid schizolaenone C ( 4) and the two known flavonoids diplacol ( 5) and 3'-prenylnaringenin ( 6) were isolated from a methanol extract of the same plant”

✓ located verbatim in the source · abstract, characters 315–544 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

A new flavonoid, schizolaenone C, and two known flavonoids were isolated from a methanol extract of Schizolaena hystrix.

Taxon
Schizolaena hystrixSchizolaena hystrixe0
Outcome
flavonoidse2
Qualifier
isolated from a methanol extracte2

Verbatim

e0

“Bioassay-guided fractionation of a crude ethanol extract from a Madagascar collection of Schizolaena hystrix”

✓ located verbatim in the source · abstract, characters 0–108 · show in text ↑
e2

“the long-chain alcohol 1-hydroxydodecan-2-one ( 7), as well as the new flavonoid schizolaenone C ( 4) and the two known flavonoids diplacol ( 5) and 3'-prenylnaringenin ( 6) were isolated from a methanol extract of the same plant”

✓ located verbatim in the source · abstract, characters 315–544 · show in text ↑