Abstract
본 연구에서는 미성숙 목화다래 추출물의 항산화능을 알아보기 위해 다래를 크기별로 구분하여 총 폴리페놀 및 플라보노이드 함량과 DPPH radical의 소거능, 아질산염 소거능, ABTS radical 소거능 및 SOD 유사활성을 측정하였다. 추출물의 페놀성 화합물과 플라보노이드 함량은 목화다래의 크기가 작을수록 높게 나타났으며, DPPH radical 소거능 및 ABTS radical의 소거능 또한 작은 크기에서 상대적으로 높은 활성을 보였다. 이는 다른 선행연구들에서와 같이 페놀함량이 높은 실험군에서 DPPH radical 소거능과 ABTS radical 소거능이 높게 나타나 유의성을 확인하였다. 아질산염 소거능은 인체 위 내부환경과 같은 pH 1.2에서는 높은 활성을 보이다가 pH 4.2에서는 점차로 활성이 떨어지는 결과를 보였으며, 중성에 가까운 pH 6.0에서는 아질산염 소거에 영향을 미치지 못하는 것으로 확인되었다. 또한 SOD 유사활성은 대조군인 ascorbic acid에 비하면 낮은 활성이었지만, 기 보고된 다른 천연물들의 효소활성과 비교하였을 때 더 높거나 비슷한 결과를 나타냈다. 이와 같이 본 실험을 통해 미성숙 목화다래의 뛰어난 항산화 활성을 확인할 수 있었으며, 이는 향후 화장품이나 기능성 식품 등에 있어서 새로운 소재개발의 가능성을 시사해주는 것으로서, 그동안 주로 천연 솜의 생산을 위해 재배되어왔던 목화의 제한적 활용성을 더욱 다양하게 해줄 것으로 기대된다. The results of the content of total polyphenol and flavonoid, DPPH (1-1-diphenyl-2-picryl-hydrazyl) radical scavenging activity, ABTS [2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)] radical scavenging activity, nitrite scavenging activity and SOD-like activity of methanol extracts from immature cotton boll are follows. The contents of total polyphenol and flavonoid compound were higher in small size cotton boll, and DPPH and ABTS radical scavenging activity also showed a relatively high activity in the small size. These results indicate that there is a correlation between phenol content and DPPH radical scavenging, ABTS radical scavenging. The test concentrations of immature cotton boll extract for measuring DPPH and ABTS radical scavenging activities were set as 1.25, 2.5, 5, 10 and 20 mg/ml. Immature cotton boll has high radical scavenging activity at the concentration of 1.25~20 mg/ml and the result showed a tendency to increase in a concentration-dependent. The nitrite scavenging activity showed high activity in the pH 1.2, and the result in the pH 4.2 showed progressively less active, and in the pH 6.0 near neutral was confirmed that does not affect the nitrite scavenging. In addition, SOD-like activity showed somewhat lower activity compared with ascorbic acid, but tended to be higher when compared with the results of the other natural substances. Through this experiment, we confirmed that immature cotton boll was excellent antioxidant activity. Therefore, it is demonstrated that the cotton suggest the possibility of development of new material for cosmetic product or functional food in the future, and is expected to make a greater usability.
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Claims 10
Claim · model-written summary
Smaller cotton bolls had higher total polyphenol and flavonoid contents.
- Taxon
- cotton
Gossypium hirsutume0 - Material
- small size cotton bolle0
- Organ / stage
- bolle0
- Outcome
- contents of total polyphenol and flavonoid compounde0
- Direction
- highere0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The contents of total polyphenol and flavonoid compound were higher in small size cotton boll”
Claim · model-written summary
Smaller cotton bolls had relatively high DPPH and ABTS radical scavenging activity.
- Taxon
- cottonGossypium hirsutumt0
- Material
- small sizee0
- Outcome
- DPPH and ABTS radical scavenging activitye0
- Direction
- relatively highe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“DPPH and ABTS radical scavenging activity also showed a relatively high activity in the small size.”
t0“Cotton Boll”
Claim · model-written summary
Phenol content correlated with DPPH radical scavenging.
- Taxon
- cottonGossypium hirsutumt0
- Compound
- phenol contente0
- Outcome
- DPPH radical scavenginge0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“there is a correlation between phenol content and DPPH radical scavenging, ABTS radical scavenging.”
t0“Cotton Boll”
Claim · model-written summary
Phenol content correlated with ABTS radical scavenging.
- Taxon
- cottonGossypium hirsutumt0
- Compound
- phenol contente0
- Outcome
- ABTS radical scavenginge0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“there is a correlation between phenol content and DPPH radical scavenging, ABTS radical scavenging.”
t0“Cotton Boll”
Claim · model-written summary
Radical scavenging activity increased with cotton boll extract concentration from 1.25 to 20 mg/ml.
- Taxon
- cottonGossypium hirsutume0
- Organ / stage
- bolle0
- Treatment
- concentration-dependente0
- Outcome
- radical scavenging activitye0
- Direction
- increasee0
- Value
- 1.25~20 mg/mle0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Immature cotton boll has high radical scavenging activity at the concentration of 1.25~20 mg/ml and the result showed a tendency to increase in a concentration-dependent.”
Claim · model-written summary
Nitrite scavenging activity was high at pH 1.2.
- Taxon
- cottonGossypium hirsutumt0
- Outcome
- nitrite scavenging activitye0
- Direction
- highe0
- Qualifier
- pH 1.2e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The nitrite scavenging activity showed high activity in the pH 1.2”
t0“Cotton Boll”
Claim · model-written summary
Nitrite scavenging activity was less active at pH 4.2.
- Taxon
- cottonGossypium hirsutumt0
- Outcome
- less activee0
- Direction
- less activee0
- Qualifier
- pH 4.2e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the result in the pH 4.2 showed progressively less active”
t0“Cotton Boll”
Claim · model-written summary
Cotton boll extract did not affect nitrite scavenging at pH 6.0.
- Taxon
- cottonGossypium hirsutumt0
- Outcome
- nitrite scavenginge0
- Direction
- does not affecte0
- Qualifier
- pH 6.0e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“in the pH 6.0 near neutral was confirmed that does not affect the nitrite scavenging.”
t0“Cotton Boll”
Claim · model-written summary
SOD-like activity was lower than ascorbic acid.
- Taxon
- cottonGossypium hirsutumt0
- Outcome
- SOD-like activitye0
- Direction
- lowere0
- Comparator
- ascorbic acide0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“SOD-like activity showed somewhat lower activity compared with ascorbic acid”
t0“Cotton Boll”
Claim · model-written summary
SOD-like activity tended to be higher than that of other natural substances.
- Taxon
- cottonGossypium hirsutumt0
- Outcome
- highere0
- Direction
- highere0
- Comparator
- the other natural substancese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“but tended to be higher when compared with the results of the other natural substances.”
t0“Cotton Boll”