Paper · 2000 · Phytotherapy Research

Antioxidant activity of Nigella sativa essential oil

M. Burits; F. Bucar

6
claims
11
verbatim quotes
1,853
citations
1
research areas
—
Not open access

Abstract

The essential oil of black cumin seeds, Nigella sativa L., was tested for a possible antioxidant activity. A rapid evaluation for antioxidants, using two TLC screening methods, showed that thymoquinone and the components carvacrol, t-anethole and 4-terpineol demonstrated respectable radical scavenging property. These four constituents and the essential oil possessed variable antioxidant activity when tested in the diphenylpicrylhydracyl assay for non-specific hydrogen atom or electron donating activity. They were also effective.OH radical scavenging agents in the assay for non-enzymatic lipid peroxidation in liposomes and the deoxyribose degradation assay. GC-MS analysis of the essential oil obtained from six different samples of Nigella sativa seeds and from a commercial fixed oil showed that the qualitative composition of the volatile compounds was almost identical. Differences were mainly restricted to the quantitative composition.

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Claims 6

Observationobservedoriginal resultmeasured

Claim · model-written summary

Thymoquinone from Nigella sativa essential oil showed respectable radical scavenging property in TLC screening.

Taxon
Nigella sativaNigella sativat0
Compound
thymoquinonee0
Outcome
respectable radical scavenging propertye0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nigella sativa
Nigella sativa · TaxonAndreHolz at English Wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“thymoquinone and the components carvacrol, t-anethole and 4-terpineol demonstrated respectable radical scavenging property”

✓ located verbatim in the source · abstract, characters 189–311 · show in text ↑
t0

“Nigella sativa”

✓ located verbatim in the source · title, characters 24–38 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Carvacrol, t-anethole and 4-terpineol from Nigella sativa essential oil showed respectable radical scavenging property in TLC screening.

Taxon
Nigella sativaNigella sativat0
Compound
carvacrol, t-anethole and 4-terpineole0
Outcome
respectable radical scavenging propertye0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nigella sativa
Nigella sativa · TaxonAndreHolz at English Wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“the components carvacrol, t-anethole and 4-terpineol demonstrated respectable radical scavenging property”

✓ located verbatim in the source · abstract, characters 206–311 · show in text ↑
t0

“Nigella sativa”

✓ located verbatim in the source · title, characters 24–38 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The four constituents and the essential oil had variable antioxidant activity in the diphenylpicrylhydracyl assay.

Taxon
Nigella sativaNigella sativat0
Outcome
variable antioxidant activitye1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nigella sativa
Nigella sativa · TaxonAndreHolz at English Wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e1

“These four constituents and the essential oil possessed variable antioxidant activity when tested in the diphenylpicrylhydracyl assay”

✓ located verbatim in the source · abstract, characters 313–446 · show in text ↑
t0

“Nigella sativa”

✓ located verbatim in the source · title, characters 24–38 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The constituents and the essential oil were effective OH radical scavengers in the liposome lipid peroxidation and deoxyribose degradation assays.

Taxon
Nigella sativaNigella sativat0
Outcome
effective.OH radical scavenging agentse2

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nigella sativa
Nigella sativa · TaxonAndreHolz at English Wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e2

“They were also effective.OH radical scavenging agents in the assay for non-enzymatic lipid peroxidation in liposomes and the deoxyribose degradation assay”

✓ located verbatim in the source · abstract, characters 509–663 · show in text ↑
t0

“Nigella sativa”

✓ located verbatim in the source · title, characters 24–38 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

GC-MS showed that the qualitative composition of the volatile compounds was almost identical across six Nigella sativa seed samples and a commercial fixed oil.

Taxon
Nigella sativaNigella sativae3
Outcome
qualitative composition of the volatile compoundse3

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nigella sativa
Nigella sativa · TaxonAndreHolz at English Wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e3

“GC-MS analysis of the essential oil obtained from six different samples of Nigella sativa seeds and from a commercial fixed oil showed that the qualitative composition of the volatile compounds was almost identical”

✓ located verbatim in the source · abstract, characters 665–879 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Differences among the samples were mainly restricted to the quantitative composition.

Taxon
Nigella sativaNigella sativat0
Outcome
quantitative compositione4

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nigella sativa
Nigella sativa · TaxonAndreHolz at English Wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e4

“Differences were mainly restricted to the quantitative composition”

✓ located verbatim in the source · abstract, characters 881–947 · show in text ↑
t0

“Nigella sativa”

✓ located verbatim in the source · title, characters 24–38 · show in text ↑