Abstract
Many bacterial diseases of plants depend on the interaction of type III effector genes of the pathogen and disease-susceptibility genes of the host. The host susceptibility genes are largely unknown. Here, we show that expression of the rice gene Os8N3, a member of the MtN3 gene family from plants and animals, is elevated upon infection by Xanthomonas oryzae pv. oryzae strain PXO99(A) and depends on the type III effector gene pthXo1. Os8N3 resides near xa13, and PXO99(A) failed to induce Os8N3 in rice lines with xa13. Silencing of Os8N3 by inhibitory RNA produced plants that were resistant to infection by strain PXO99(A) yet remained susceptible to other strains of the pathogen. The effector gene avrXa7 from strain PXO86 enabled PXO99(A) compatibility on either xa13- or Os8N3-silenced plants. The findings indicate that Os8N3 is a host susceptibility gene for bacterial blight targeted by the type III effector PthXo1. The results support the hypothesis that X. oryzae pv. oryzae commandeers the regulation of otherwise developmentally regulated host genes to induce a state of disease susceptibility. Furthermore, the results support a model in which the pathogen induces disease susceptibility in a gene-for-gene manner.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 7
Claim · model-written summary
Rice Os8N3 expression rises after PXO99(A) infection and depends on pthXo1.
- Taxon
- rice
Oryza sativae0 - Interactor
- Xanthomonas oryzae pv. oryzae
Xanthomonas oryzae pv. oryzaee0pathogen - Gene
- Os8N3e0
- Outcome
- expression of the rice gene Os8N3e0
- Direction
- elevatede0
- Qualifier
- depends on the type III effector gene pthXo1e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“expression of the rice gene Os8N3, a member of the MtN3 gene family from plants and animals, is elevated upon infection by Xanthomonas oryzae pv. oryzae strain PXO99(A) and depends on the type III effector gene pthXo1”
Claim · model-written summary
Os8N3 resides near xa13.
- Taxon
- riceOryza sativat0
- Gene
- Os8N3e0
- Outcome
- resides near xa13e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Os8N3 resides near xa13”
t0“rice”
Claim · model-written summary
PXO99(A) did not induce Os8N3 in rice lines with xa13.
- Taxon
- riceOryza sativae0
- Material
- rice lines with xa13e0
- Interactor
- PXO99(A)e0pathogen
- Gene
- Os8N3e0
- Outcome
- failed to induce Os8N3e0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“PXO99(A) failed to induce Os8N3 in rice lines with xa13”
Claim · model-written summary
Os8N3 silencing conferred resistance to PXO99(A).
- Taxon
- riceOryza sativat0
- Treatment
- Silencing of Os8N3 by inhibitory RNAe0
- Interactor
- PXO99(A)e0pathogen
- Gene
- Os8N3e0
- Outcome
- resistant to infection by strain PXO99(A)e0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Silencing of Os8N3 by inhibitory RNA produced plants that were resistant to infection by strain PXO99(A)”
t0“rice”
Claim · model-written summary
Os8N3 silenced plants remained susceptible to other pathogen strains.
- Taxon
- riceOryza sativat0
- Interactor
- pathogene0pathogen
- Outcome
- susceptible to other strains of the pathogene0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“yet remained susceptible to other strains of the pathogen”
t0“rice”
Claim · model-written summary
avrXa7 enabled PXO99(A) compatibility on xa13 or Os8N3 silenced rice.
- Taxon
- riceOryza sativat0
- Treatment
- avrXa7e0
- Interactor
- PXO99(A)e0pathogen
- Gene
- avrXa7e0
- Outcome
- PXO99(A) compatibilitye0
- Qualifier
- either xa13- or Os8N3-silenced plantse0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The effector gene avrXa7 from strain PXO86 enabled PXO99(A) compatibility on either xa13- or Os8N3-silenced plants”
t0“rice”
Claim · model-written summary
The authors identify Os8N3 as a susceptibility gene targeted by PthXo1.
- Taxon
- riceOryza sativat0
- Gene
- Os8N3e0
- Outcome
- host susceptibility gene for bacterial blighte0
- Qualifier
- targeted by the type III effector PthXo1e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Os8N3 is a host susceptibility gene for bacterial blight targeted by the type III effector PthXo1”
t0“rice”
The same questions in other papers
loss of function · disease · Oryza sativa (rice)Positive and negative results
85 papers in the same direction as this paper · 68 in the opposite direction
- negative
- positive
- positive
150 papers more in this group
See all 154 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.