Abstract
Surprisingly, few studies have described evolutionary rate variation among plant nuclear genes, with little investigation of the causes of rate variation. Here, we describe evolutionary rates for 11,492 ortholog pairs between Arabidopsis thaliana and A. lyrata and investigate possible contributors to rate variation among these genes. Rates of evolution at synonymous sites vary along chromosomes, suggesting that mutation rates vary on genomic scales, perhaps as a function of recombination rate. Rates of evolution at nonsynonymous sites correlate most strongly with expression patterns, but they also vary as to whether a gene is duplicated and retained after a whole-genome duplication (WGD) event. WGD genes evolve more slowly, on average, than nonduplicated genes and non-WGD duplicates. We hypothesize that levels and patterns of expression are not only the major determinants that explain nonsynonymous rate variation among genes but also a critical determinant of gene retention after duplication.
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 7
Claim · model-written summary
Rates of evolution at synonymous sites vary along Arabidopsis chromosomes.
- Taxon
- Arabidopsis
Arabidopsist0 - Outcome
- Rates of evolution at synonymous sitese0
- Qualifier
- vary along chromosomese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Rates of evolution at synonymous sites vary along chromosomes”
t0“Arabidopsis”
Claim · model-written summary
Synonymous-site rate variation suggests mutation rates vary on genomic scales, perhaps as a function of recombination rate.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- mutation ratese0
- Qualifier
- perhaps as a function of recombination ratee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“suggesting that mutation rates vary on genomic scales, perhaps as a function of recombination rate”
t0“Arabidopsis”
Claim · model-written summary
Rates of evolution at nonsynonymous sites correlate most strongly with expression patterns.
- Taxon
- ArabidopsisArabidopsist0
- Gene
- expression patternse0
- Outcome
- Rates of evolution at nonsynonymous sitese0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Rates of evolution at nonsynonymous sites correlate most strongly with expression patterns”
t0“Arabidopsis”
Claim · model-written summary
Nonsynonymous rates also vary with whether a gene is duplicated and retained after a whole-genome duplication event.
- Taxon
- ArabidopsisArabidopsist0
- Gene
- a gene is duplicated and retained after a whole-genome duplication (WGD) evente0
- Outcome
- they also varye0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“they also vary as to whether a gene is duplicated and retained after a whole-genome duplication (WGD) event”
t0“Arabidopsis”
Claim · model-written summary
WGD genes evolve more slowly on average than nonduplicated genes.
- Taxon
- ArabidopsisArabidopsist0
- Gene
- WGD genese0
- Outcome
- evolvee0
- Direction
- more slowlye0
- Comparator
- nonduplicated genese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“WGD genes evolve more slowly, on average, than nonduplicated genes and non-WGD duplicates”
t0“Arabidopsis”
Claim · model-written summary
WGD genes evolve more slowly on average than non-WGD duplicates.
- Taxon
- ArabidopsisArabidopsist0
- Gene
- WGD genese0
- Outcome
- evolvee0
- Direction
- more slowlye0
- Comparator
- non-WGD duplicatese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“WGD genes evolve more slowly, on average, than nonduplicated genes and non-WGD duplicates”
t0“Arabidopsis”
Claim · model-written summary
The authors hypothesize that expression levels and patterns are the major determinants of nonsynonymous rate variation and a critical determinant of gene retention after duplication.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- nonsynonymous rate variation among genese0
- Qualifier
- levels and patterns of expressione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“levels and patterns of expression are not only the major determinants that explain nonsynonymous rate variation among genes but also a critical determinant of gene retention after duplication”
t0“Arabidopsis”