Abstract
The chemical study of Alvaradoa amorphoides led to the isolation of four major constituents: chrysophanol (1), β-sitosterol (2), atraric acid (3), and 17-octadecen-6-ynoic acid (4). All compounds were evaluated on in vitro cytotoxic and antiproliferative assays. Atraric acid and 17-octadecen-6-ynoic acid showed cytotoxic activity. Additionally, compound 4 exhibited cytotoxic activity showing a certain degree of selectivity against cancer cell lines.
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Claims 4
Claim · model-written summary
Chrysophanol, β-sitosterol and atraric acid were isolated from Alvaradoa amorphoides.
- Taxon
- Alvaradoa amorphoides
Alvaradoa amorphoidest0 - Outcome
- chrysophanol (1), β-sitosterol (2), atraric acid (3)e0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Alvaradoa amorphoides”
e0“isolation of four major constituents: chrysophanol (1), β-sitosterol (2), atraric acid (3), and 17-octadecen-6-ynoic acid (4)”
Claim · model-written summary
17-octadecen-6-ynoic acid was isolated from Alvaradoa amorphoides.
- Taxon
- Alvaradoa amorphoidesAlvaradoa amorphoidest0
- Outcome
- 17-octadecen-6-ynoic acide0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Alvaradoa amorphoides”
e0“17-octadecen-6-ynoic acid (4)”
Claim · model-written summary
Atraric acid showed cytotoxic activity.
- Taxon
- Alvaradoa amorphoidesAlvaradoa amorphoidest0
- Outcome
- Atraric acide0
- Qualifier
- cytotoxic activitye0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Alvaradoa amorphoides”
e0“Atraric acid and 17-octadecen-6-ynoic acid showed cytotoxic activity”
Claim · model-written summary
17-octadecen-6-ynoic acid showed cytotoxic activity with some selectivity against cancer cell lines.
- Taxon
- Alvaradoa amorphoidesAlvaradoa amorphoidest0
- Outcome
- cytotoxic activitye0
- Qualifier
- a certain degree of selectivity against cancer cell linese1
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Alvaradoa amorphoides”
e0“17-octadecen-6-ynoic acid showed cytotoxic activity”
e1“compound 4 exhibited cytotoxic activity showing a certain degree of selectivity against cancer cell lines”