Paper · 2016 · Natural Product Research

Antimicrobial and antioxidant activity of the essential oil from the Carpathian Thymus alternans Klokov

Luca A. Vitali; Stefano Dall’Acqua; Filippo Maggi; et al.

4
claims
6
verbatim quotes
19
citations
2
research areas
—
Not open access

Abstract

The genus Thymus includes several species that are used as flavouring, food preservative as well as in cosmetics. Their secondary metabolites have been extensively studied for pharmacological effects. Nonetheless, some species are neglected and deserve to be explored for chemical composition and biological activities. This is the case with Thymus alternans, a Carpathian bush used as a food additive and for the preparation of a traditional herbal medicine. In this work, we have analysed the chemical composition of T. alternans essential oil by GC and GC-MS and evaluated its antimicrobial and antioxidant activity by disc diffusion, DPPH, ABTS and FRAP methods, respectively. Results showed that T. alternans belongs to the nerolidol chemotype, being rich of this sesquiterpene alcohol (15.8%) which might contribute to the antimicrobial (particularly effective on C. albicans growth) and antioxidant (weak inhibition on ABTS radical and reducing power) activities observed.

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Claims 4

Observationobservedoriginal resultmeasured

Claim · model-written summary

Thymus alternans belongs to the nerolidol chemotype.

Taxon
T. alternansThymus alternanse0
Outcome
nerolidol chemotypee0

Verbatim

e0

“Results showed that T. alternans belongs to the nerolidol chemotype, being rich of this sesquiterpene alcohol (15.8%)”

✓ located verbatim in the source · abstract, characters 681–798 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The essential oil of Thymus alternans contains 15.8% of the sesquiterpene alcohol nerolidol.

Taxon
T. alternansThymus alternanse0
Outcome
sesquiterpene alcohole0
Value
15.8%e0

Verbatim

e0

“Results showed that T. alternans belongs to the nerolidol chemotype, being rich of this sesquiterpene alcohol (15.8%)”

✓ located verbatim in the source · abstract, characters 681–798 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The essential oil of Thymus alternans was particularly effective on C. albicans growth.

Taxon
T. alternansThymus alternanse0
Interactor
C. albicanse1other
Outcome
C. albicans growthe1
Direction
particularly effectivee1

Verbatim

e0

“Results showed that T. alternans belongs to the nerolidol chemotype, being rich of this sesquiterpene alcohol (15.8%)”

✓ located verbatim in the source · abstract, characters 681–798 · show in text ↑
e1

“antimicrobial (particularly effective on C. albicans growth)”

✓ located verbatim in the source · abstract, characters 829–889 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The essential oil of Thymus alternans showed weak antioxidant inhibition in the ABTS radical and reducing power assays.

Taxon
T. alternansThymus alternanse0
Outcome
antioxidante2
Direction
weak inhibitione2
Qualifier
ABTS radical and reducing powere2

Verbatim

e0

“Results showed that T. alternans belongs to the nerolidol chemotype, being rich of this sesquiterpene alcohol (15.8%)”

✓ located verbatim in the source · abstract, characters 681–798 · show in text ↑
e2

“antioxidant (weak inhibition on ABTS radical and reducing power)”

✓ located verbatim in the source · abstract, characters 894–958 · show in text ↑