Abstract
Abstract Hexane extracts of Heracleum verticillatum , H. sibiricum , H. angustisectum , and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α ‐amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H‐NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum , respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 m m , respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α ‐amylase.
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Claims 10
Claim · model-written summary
Pimpinellin was the main component of roots in all studied species.
HeracleumOrganisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Pimpinellin was found to be the main component in the roots of all studied species”
t0“Heracleum verticillatum, Heracleum sibiricum”
Claim · model-written summary
Bergapten was a major fruit compound of H. sibiricum.
- Taxon
- H. sibiricum
Heracleum sphondylium subsp. sibiricume0 - Organ / stage
- fruitse0
- Outcome
- Bergaptene0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum , respectively”
Claim · model-written summary
Imperatorin was a major fruit compound of H. verticillatum.
- Taxon
- H. verticillatum
Heracleum sphondylium subsp. verticillatume0 - Organ / stage
- fruitse0
- Outcome
- imperatorine0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum , respectively”
Claim · model-written summary
Byakangelicol dominated fruit of H. angustisectum.
- Taxon
- H. angustisectumHeracleum angustisectume0
- Organ / stage
- fruitse0
- Outcome
- byakangelicol dominatede0
Verbatim
e0“byakangelicol dominated in H. angustisectum and H. ternatum fruits”
Claim · model-written summary
Byakangelicol dominated fruit of H. ternatum.
- Taxon
- H. ternatumHeracleum sphondylium subsp. ternatume0
- Organ / stage
- fruitse0
- Outcome
- byakangelicol dominatede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“byakangelicol dominated in H. angustisectum and H. ternatum fruits”
Claim · model-written summary
H. angustisectum leaf and fruit extracts had the highest DPPH radical scavenging activity, with IC50 0.58 mg/mL.
Verbatim
e0“The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 m m , respectively)”
Claim · model-written summary
H. angustisectum leaf and fruit extracts had the highest TEAC, at 1.83 m m.
Verbatim
e0“The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 m m , respectively)”
Claim · model-written summary
H. verticillatum root extract was most effective against acetylcholinesterase with IC50 0.30 mg/mL.
- Taxon
- H. verticillatumHeracleum sphondylium subsp. verticillatume0
- Organ / stage
- roote0
- Outcome
- effective against acetylcholinesterasee0
- Direction
- most effectivee0
- Value
- 0.30e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively)”
Claim · model-written summary
H. angustisectum root extract was most effective against acetylcholinesterase with IC50 0.34 mg/mL.
Verbatim
e0“The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively)”
Claim · model-written summary
The studied extracts had no or weak α-amylase inhibition, up to 29.7%.
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α ‐amylase”
t0“Heracleum verticillatum, Heracleum sibiricum”