Abstract
Helianthus species are North American members of the Asteraceae, several of which have been used as traditional medicines by Native Americans. The aerial parts of two cultivars of Helianthus annuus, “Chianti” and “Mammoth”, and wild-growing H. strumosus, were collected from locations in north Alabama. The essential oils were obtained by hydrodistillation and analyzed by gas chromatography—mass spectrometry. The Helianthus essential oils were dominated by monoterpene hydrocarbons, in particular α-pinene (50.65%, 48.91%, and 58.65%, respectively), sabinene (6.81%, 17.01%, and 1.91%, respectively), β-pinene (5.79%, 3.27%, and 4.52%, respectively), and limonene (7.2%, 7.1%, and 3.8%, respectively). The essential oils were screened against three opportunistic pathogenic fungal species, Aspergillus niger, Candida albicans, and Cryptococcus neoformans. The most sensitive fungus was C. neoformans with minimum inhibitory concentration (MIC) values of 78, 156, and 78 μg/mL, respectively.
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Claims 6
Claim · model-written summary
The oils were dominated by monoterpene hydrocarbons.
- Taxon
- Helianthus
Helianthuse0 - Outcome
- dominated by monoterpene hydrocarbonse0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The Helianthus essential oils were dominated by monoterpene hydrocarbons”
Claim · model-written summary
Alpha-pinene percentages were 50.65%, 48.91%, and 58.65%, respectively.
Not reportedTaxon
Verbatim
e0“α-pinene (50.65%, 48.91%, and 58.65%, respectively)”
Claim · model-written summary
Sabinene percentages were 6.81%, 17.01%, and 1.91%, respectively.
Not reportedTaxon
Verbatim
e0“sabinene (6.81%, 17.01%, and 1.91%, respectively)”
Claim · model-written summary
Beta-pinene percentages were 5.79%, 3.27%, and 4.52%, respectively.
Not reportedTaxon
Verbatim
e0“β-pinene (5.79%, 3.27%, and 4.52%, respectively)”
Claim · model-written summary
Limonene percentages were 7.2%, 7.1%, and 3.8%, respectively.
Not reportedTaxon
Verbatim
e0“limonene (7.2%, 7.1%, and 3.8%, respectively)”
Claim · model-written summary
Cryptococcus neoformans was most sensitive to the oils, with MICs of 78, 156, and 78 μg/mL.
- Interactor
- C. neoformans
Cryptococcus neoformanse0other - Outcome
- C. neoformans with minimum inhibitory concentration (MIC)e0
- Direction
- most sensitivee0
- Value
- 78, 156, and 78 μg/mLe0
Not reportedTaxon
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The most sensitive fungus was C. neoformans with minimum inhibitory concentration (MIC) values of 78, 156, and 78 μg/mL, respectively.”