Abstract
Pharmacognosy Research,2019,11,3,244-247.DOI:10.4103/pr.pr_180_18Published:August 2019Type:Original ArticleAuthors:Zead Helmi Abudayeh, Ihab Ibrahim Al Khalifa, Shaimaa M. Mohammed, and Asser Ashraf Ahmad Author(s) affiliations:Zead Helmi Abudayeh1, Ihab Ibrahim Al Khalifa2, Shaimaa M Mohammed3, Asser Ashraf Ahmad1 1Department of Applied Pharmaceutical Science and Clinical Pharmacy, Faculty of Pharmacy, Al-Isra University, Amman, Jordan. 2Department of Pharmacy, Al-Rasheed University College, Baghdad, Iraq. 3Department of Pharmacy, Al-Mustaqbal University College, Babylon, Iraq. Abstract:Background: There is an increasing interest in the antioxidant measurement of some plant constituents. Plant component, especially fruit, has antioxidant components which are safe, economic, and powerful to reduce oxidative stress and replace synthetic ones. Objectives: To quantitatively measure the flavonoids, Vitamin C, and carotenoid content of hydroalcoholic extract and to estimate the antioxidant activity of pomelo peel extract (PPE) and minimum inhibitory concentration 50% (IC50) of the extract using 2,2‑diphenyl‑1‑picrylhydrazyl (DPPH) ethanolic solution. Materials and Methods: Hydroalcoholic PPE was prepared; total flavonoids using aluminum chloride method, Vitamin C using thiourea and 2,4‑dinitrophenylhydrazine method, and carotenoid content of the extract were estimated using 95% ethanol solution. All measurements were estimated using ultraviolet–visible spectrophotometer. Antioxidant activity and IC50 of PPE were measured using DPPH method. Results: Flavonoids, Vitamin C, and carotenoid content were measured as 21.20 mg/100 g, 15.13 mg/100 g, and 62.98 μg/g, respectively, of dry PPE. The DPPH radical scavenging activity exhibits a significant dose‑dependent inhibition of DPPH radical color, with IC50 being at a concentration of 68.55 μg/ml of the extract, comparable to 55.87 μg/ml IC50 of Vitamin C standard antioxidant. Conclusion: From the study results, we could conclude that pomelo peel possesses high antioxidant properties and it is potentially rich sources of natural antioxidants. Keywords:2, 2‑diphenyl‑1‑picrylhydrazyl, Antioxidant capacity, Ascorbic acid, Citrus maxima., FlavonoidsView:PDF (929.35 KB)
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Claims 6
Claim · model-written summary
Flavonoid content of dry pomelo peel extract was measured as 21.20 mg/100 g.
- Taxon
- pomelo
Citrus maximat0 - Organ / stage
- peelt0
- Outcome
- Flavonoidse0
- Value
- 21.20 mg/100 ge0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“pomelo peel”
e0“Flavonoids, Vitamin C, and carotenoid content were measured as 21.20 mg/100 g, 15.13 mg/100 g, and 62.98 μg/g, respectively, of dry PPE”
Claim · model-written summary
Vitamin C content of dry pomelo peel extract was measured as 15.13 mg/100 g.
- Taxon
- pomeloCitrus maximat0
- Organ / stage
- peelt0
- Outcome
- Vitamin Ce0
- Value
- 15.13 mg/100 ge0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“pomelo peel”
e0“Flavonoids, Vitamin C, and carotenoid content were measured as 21.20 mg/100 g, 15.13 mg/100 g, and 62.98 μg/g, respectively, of dry PPE”
Claim · model-written summary
Carotenoid content of dry pomelo peel extract was measured as 62.98 μg/g.
- Taxon
- pomeloCitrus maximat0
- Organ / stage
- peelt0
- Outcome
- carotenoid contente0
- Value
- 62.98 μg/ge0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“pomelo peel”
e0“Flavonoids, Vitamin C, and carotenoid content were measured as 21.20 mg/100 g, 15.13 mg/100 g, and 62.98 μg/g, respectively, of dry PPE”
Claim · model-written summary
DPPH radical scavenging activity of pomelo peel extract was significant.
- Taxon
- pomeloCitrus maximat0
- Organ / stage
- peelt0
- Outcome
- DPPH radical scavenging activitye0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“pomelo peel”
e0“The DPPH radical scavenging activity exhibits a significant”
Claim · model-written summary
The IC50 of pomelo peel extract was 68.55 μg/ml, comparable to 55.87 μg/ml for the Vitamin C standard.
- Taxon
- pomeloCitrus maximat0
- Organ / stage
- peelt0
- Outcome
- IC50e0
- Value
- 68.55 μg/mle0
- Qualifier
- 55.87 μg/ml IC50e0
- Comparator
- Vitamin C standard antioxidante0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“pomelo peel”
e0“IC50 being at a concentration of 68.55 μg/ml of the extract, comparable to 55.87 μg/ml IC50 of Vitamin C standard antioxidant”
Claim · model-written summary
The authors conclude that pomelo peel possesses high antioxidant properties.
- Taxon
- pomeloCitrus maximat0
- Organ / stage
- peelt0
- Outcome
- high antioxidant propertiese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“pomelo peel”
e0“we could conclude that pomelo peel possesses high antioxidant properties”