Abstract
Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a global threat to wheat production. Aegilops tauschii, one of the wheat progenitors, carries the YrAS2388 locus for resistance to Pst on chromosome 4DS. We reveal that YrAS2388 encodes a typical nucleotide oligomerization domain-like receptor (NLR). The Pst-resistant allele YrAS2388R has duplicated 3' untranslated regions and is characterized by alternative splicing in the nucleotide-binding domain. Mutation of the YrAS2388R allele disrupts its resistance to Pst in synthetic hexaploid wheat; transgenic plants with YrAS2388R show resistance to eleven Pst races in common wheat and one race of P. striiformis f. sp. hordei in barley. The YrAS2388R allele occurs only in Ae. tauschii and the Ae. tauschii-derived synthetic wheat; it is absent in 100% (n = 461) of common wheat lines tested. The cloning of YrAS2388R will facilitate breeding for stripe rust resistance in wheat and other Triticeae species.
Abstract from the paper’s OpenAlex record; open copy licensed cc-by. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 8
Claim · model-written summary
In Aegilops tauschii, YrAS2388 encodes a nucleotide oligomerization domain-like receptor.
- Taxon
- Aegilops tauschii
.jpg?width=60)
Aegilops tauschiie0 - Gene
- YrAS2388e0
- Outcome
- encodes a typical nucleotide oligomerization domain-like receptor (NLR)e0
Not reportedOrgan / stage
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
.jpg?width=500)
Verbatim
e0“Aegilops tauschii, one of the wheat progenitors, carries the YrAS2388 locus for resistance to Pst on chromosome 4DS. We reveal that YrAS2388 encodes a typical nucleotide oligomerization domain-like receptor (NLR)”
Claim · model-written summary
The resistant YrAS2388R allele has duplicated 3′ untranslated regions and alternative splicing in the nucleotide-binding domain.
- Taxon
- wheat and barley
.jpg?width=60)
Hordeum vulgare
Triticum aestivumt0 - Gene
- YrAS2388Re0
- Outcome
- duplicated 3' untranslated regions and is characterized by alternative splicing in the nucleotide-binding domaine0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
.jpg?width=500)
Verbatim
e0“The Pst-resistant allele YrAS2388R has duplicated 3' untranslated regions and is characterized by alternative splicing in the nucleotide-binding domain”
t0“wheat and barley”
Claim · model-written summary
Mutation of YrAS2388R disrupted resistance to Pst in synthetic hexaploid wheat.
- Taxon
- wheatTriticum aestivume0
- Material
- synthetic hexaploid wheate0
- Treatment
- Mutation of the YrAS2388R allelee0
- Interactor
- Pste0pathogen
- Gene
- YrAS2388Re0
- Outcome
- resistance to Pste0
- Direction
- disruptse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Mutation of the YrAS2388R allele disrupts its resistance to Pst in synthetic hexaploid wheat”
Claim · model-written summary
Transgenic common wheat with YrAS2388R resisted eleven Pst races.
- Taxon
- common wheatTriticum aestivume0
- Material
- transgenic plantse0
- Treatment
- transgenic plants with YrAS2388Re0
- Interactor
- Pste0pathogen
- Gene
- YrAS2388Re0
- Outcome
- resistance to eleven Pst racese0
- Value
- eleven Pst racese0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“transgenic plants with YrAS2388R show resistance to eleven Pst races in common wheat”
Claim · model-written summary
Transgenic barley with YrAS2388R resisted one race of P. striiformis f. sp. hordei.
- Taxon
- barleyHordeum vulgaree0
- Material
- transgenic plantse0
- Treatment
- transgenic plants with YrAS2388Re0
- Interactor
- P. striiformis f. sp. hordei
Puccinia striiformis f. sp. hordeie0pathogen - Gene
- YrAS2388Re0
- Outcome
- one race of P. striiformis f. sp. hordeie0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“transgenic plants with YrAS2388R show resistance to eleven Pst races in common wheat and one race of P. striiformis f. sp. hordei in barley”
Claim · model-written summary
YrAS2388R occurred only in Ae. tauschii and Ae. tauschii-derived synthetic wheat, and was absent in all 461 common wheat lines tested.
Verbatim
e0“The YrAS2388R allele occurs only in Ae. tauschii and the Ae. tauschii-derived synthetic wheat; it is absent in 100% (n = 461) of common wheat lines tested”
Claim · model-written summary
YrAS2388R was absent in all 461 common wheat lines tested.
- Taxon
- common wheatTriticum aestivume0
- Gene
- YrAS2388Re0
- Outcome
- absent in 100% (n = 461) of common wheat lines testede0
- Value
- 100% (n = 461)e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The YrAS2388R allele occurs only in Ae. tauschii and the Ae. tauschii-derived synthetic wheat; it is absent in 100% (n = 461) of common wheat lines tested”
Claim · model-written summary
The authors expect cloning YrAS2388R to facilitate stripe rust resistance breeding in wheat and other Triticeae.
- Taxon
- wheatTriticum aestivume0
- Gene
- YrAS2388Re0
- Outcome
- breeding for stripe rust resistance in wheat and other Triticeae speciese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The cloning of YrAS2388R will facilitate breeding for stripe rust resistance in wheat and other Triticeae species”
The same questions in other papers
loss of function · disease · Triticum aestivum (wheat)Positive and negative results
95 papers in the same direction as this paper · 81 in the opposite direction
- positive
- negative
- positive
173 papers more in this group
See all 177 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.