Abstract
Bersama abyssinica is one of the medicinal plants used traditionally to treat various diseases such as leprosy, wound, diarrhea, fever, eye disease, rabies and tumor/cancer. Phytochemical screening test of dichloromethane/methanol (1:1) and methanol extracts revealed the presence of glycosides, alkaloids, tannins, flavanoids, saponins, terpenoids, steroids and phytosterols. Silica gel column chromatography separation of dichloromethane/methanol (1:1) root extracts afforded β-sitosterol (1), 7-hydroxysitosterol (2) and 2-methylamino-butyric acid (3) of which the latter is isolated for the first time from natural source. The crude extracts and isolated compounds were screened for in vitro antibacterial activity against strains of Salmonella thphimurium, Escherichia coli, Bacillus subtilis and Staphylococcus aureus. Dichloromethane/methanol (1:1) extract, methanol extract and β-sitosterol (1) showed moderate activity against E. coli and S. aureus (zone of inhibition 13±0, 13±2 and 12.6±0.48, respectively) and (zone of inhibition 13.6±0.55, 12±2, and 12.5±0.5 mm, respectively) compared to ciprofloxacin (28.6±1.25 and 26±5.1 mm) at 0.5 mg/mL. The structures of compounds were determined by spectroscopic techniques (IR and NMR) and comparison with literature report.
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Claims 8
Claim · model-written summary
Screening found glycosides, alkaloids and tannins.
- Taxon
- Bersama abyssinica
Bersama abyssinicae0 - Outcome
- glycosides, alkaloids, tanninse1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“revealed the presence of glycosides, alkaloids, tannins, flavanoids, saponins, terpenoids, steroids and phytosterols”
Claim · model-written summary
Screening found flavanoids, saponins and terpenoids.
- Taxon
- Bersama abyssinicaBersama abyssinicae0
- Outcome
- flavanoids, saponins, terpenoidse1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“revealed the presence of glycosides, alkaloids, tannins, flavanoids, saponins, terpenoids, steroids and phytosterols”
Claim · model-written summary
Screening found steroids and phytosterols.
- Taxon
- Bersama abyssinicaBersama abyssinicae0
- Outcome
- steroids and phytosterolse1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“revealed the presence of glycosides, alkaloids, tannins, flavanoids, saponins, terpenoids, steroids and phytosterols”
Claim · model-written summary
The root extract yielded β-sitosterol.
- Taxon
- Bersama abyssinicaBersama abyssinicae0
- Organ / stage
- roote1
- Outcome
- β-sitosterole1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“root extracts afforded β-sitosterol (1), 7-hydroxysitosterol (2) and 2-methylamino-butyric acid (3)”
Claim · model-written summary
The root extract yielded 7-hydroxysitosterol.
- Taxon
- Bersama abyssinicaBersama abyssinicae0
- Organ / stage
- roote1
- Outcome
- 7-hydroxysitosterole1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“root extracts afforded β-sitosterol (1), 7-hydroxysitosterol (2) and 2-methylamino-butyric acid (3)”
Claim · model-written summary
The root extract yielded 2-methylamino-butyric acid, reported as its first isolation from a natural source.
- Taxon
- Bersama abyssinicaBersama abyssinicae0
- Outcome
- 2-methylamino-butyric acide1
- Qualifier
- first time from natural sourcee1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“2-methylamino-butyric acid (3) of which the latter is isolated for the first time from natural source”
Claim · model-written summary
Extracts and β-sitosterol showed moderate antibacterial activity against E. coli.
- Taxon
- Bersama abyssinicaBersama abyssinicae0
- Outcome
- moderate activity against E. colie1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“Dichloromethane/methanol (1:1) extract, methanol extract and β-sitosterol (1) showed moderate activity against E. coli and S. aureus”
Claim · model-written summary
Extracts and β-sitosterol showed moderate antibacterial activity against S. aureus.
- Taxon
- Bersama abyssinicaBersama abyssinicae0
- Outcome
- moderate activity against E. coli and S. aureuse1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bersama abyssinica”
e1“Dichloromethane/methanol (1:1) extract, methanol extract and β-sitosterol (1) showed moderate activity against E. coli and S. aureus”